Strategies for Efficient Targeting of Tumor Collagen for Cancer Therapy

Strategies for Efficient Targeting of Tumor Collagen for Cancer Therapy

The tumor stroma, which comprises stromal cells and non-cellular elements, is a critical component of the tumor microenvironment (TME). The dynamic interactions between the tumor cells and the stroma may promote tumor progression and metastasis and dictate resistance to established cancer therapies....

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Bibliographic Details
Main Authors: Silvia Baldari, Francesca Di Modugno, Paola Nisticò, Gabriele Toietta
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
collagen
tumor microenvironment
extracellular matrix
cancer-associated fibroblasts
cancer therapy
stromal cells
Online Access:https://www.mdpi.com/2072-6694/14/19/4706

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