Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report
Abstract Background Rhabdomyosarcoma (RMS), a malignant neoplasm that normally differentiates to form striated muscle, is the most common type of childhood soft tissue sarcoma. However, it infrequently occurs in adults and is uncommon in the liver. We herein report a case of RMS of the liver in an a...
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| Format: | Article |
| Language: | English |
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BMC
2020-04-01
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| Series: | BMC Surgery |
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| Online Access: | http://link.springer.com/article/10.1186/s12893-020-00742-7 |
| _version_ | 1830288268509315072 |
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| author | Mitsuyoshi Okazaki Hidehiro Tajima Yoshinao Ohbatake Hiroyuki Shinbashi Shinichi Nakanuma Isamu Makino Itasu Ninomiya Sachio Fushida Koushiro Ohtsubo Tetsuo Ohta |
| author_facet | Mitsuyoshi Okazaki Hidehiro Tajima Yoshinao Ohbatake Hiroyuki Shinbashi Shinichi Nakanuma Isamu Makino Itasu Ninomiya Sachio Fushida Koushiro Ohtsubo Tetsuo Ohta |
| author_sort | Mitsuyoshi Okazaki |
| collection | DOAJ |
| description | Abstract Background Rhabdomyosarcoma (RMS), a malignant neoplasm that normally differentiates to form striated muscle, is the most common type of childhood soft tissue sarcoma. However, it infrequently occurs in adults and is uncommon in the liver. We herein report a case of RMS of the liver in an adult. Case presentation A 73-year-old woman was admitted to our institution for investigation of a hepatic mass. She had been followed for primary biliary cirrhosis for the past 20 years. A contrast-enhanced computed tomography scan of the abdomen showed a 12- × 10-cm heterogeneous low-density mass lesion containing cystic and solid components. A percutaneous liver biopsy was performed, and poorly differentiated cancer containing an RMS cell-like component was observed. The patient was diagnosed with RMS of the liver, and open surgery with right hepatic lobectomy was performed. Histopathological examination confirmed a diagnosis of pleomorphic RMS of the liver. The patient died of rapid progression of the tumor 6 months after the operation. Conclusions The tumor site in the present case is rare. The details of this case add to the current evidence base regarding establishment of the standard diagnosis and treatment of this rare condition. We recommend consideration of RMS as a differential diagnosis for hepatic tumors. |
| first_indexed | 2024-12-19T04:32:51Z |
| format | Article |
| id | doaj.art-84fd516b2876455a95bd5668c93acf21 |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-12-19T04:32:51Z |
| publishDate | 2020-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-84fd516b2876455a95bd5668c93acf212022-12-21T20:35:50ZengBMCBMC Surgery1471-24822020-04-012011610.1186/s12893-020-00742-7Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case reportMitsuyoshi Okazaki0Hidehiro Tajima1Yoshinao Ohbatake2Hiroyuki Shinbashi3Shinichi Nakanuma4Isamu Makino5Itasu Ninomiya6Sachio Fushida7Koushiro Ohtsubo8Tetsuo Ohta9Division of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa UniversityDivision of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa UniversityDivision of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa UniversityDivision of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa UniversityDivision of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa UniversityDivision of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa UniversityDivision of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa UniversityDivision of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa UniversityDivision of Medical Oncology Cancer Research Institute, Kanazawa UniversityDivision of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa UniversityAbstract Background Rhabdomyosarcoma (RMS), a malignant neoplasm that normally differentiates to form striated muscle, is the most common type of childhood soft tissue sarcoma. However, it infrequently occurs in adults and is uncommon in the liver. We herein report a case of RMS of the liver in an adult. Case presentation A 73-year-old woman was admitted to our institution for investigation of a hepatic mass. She had been followed for primary biliary cirrhosis for the past 20 years. A contrast-enhanced computed tomography scan of the abdomen showed a 12- × 10-cm heterogeneous low-density mass lesion containing cystic and solid components. A percutaneous liver biopsy was performed, and poorly differentiated cancer containing an RMS cell-like component was observed. The patient was diagnosed with RMS of the liver, and open surgery with right hepatic lobectomy was performed. Histopathological examination confirmed a diagnosis of pleomorphic RMS of the liver. The patient died of rapid progression of the tumor 6 months after the operation. Conclusions The tumor site in the present case is rare. The details of this case add to the current evidence base regarding establishment of the standard diagnosis and treatment of this rare condition. We recommend consideration of RMS as a differential diagnosis for hepatic tumors.http://link.springer.com/article/10.1186/s12893-020-00742-7Pleomorphic rhabdomyosarcomaHeterogeneous mass in liverRight hepatic lobectomyCase report |
| spellingShingle | Mitsuyoshi Okazaki Hidehiro Tajima Yoshinao Ohbatake Hiroyuki Shinbashi Shinichi Nakanuma Isamu Makino Itasu Ninomiya Sachio Fushida Koushiro Ohtsubo Tetsuo Ohta Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report BMC Surgery Pleomorphic rhabdomyosarcoma Heterogeneous mass in liver Right hepatic lobectomy Case report |
| title | Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report |
| title_full | Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report |
| title_fullStr | Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report |
| title_full_unstemmed | Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report |
| title_short | Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report |
| title_sort | pleomorphic rhabdomyosarcoma of the liver in an adult a rare case report |
| topic | Pleomorphic rhabdomyosarcoma Heterogeneous mass in liver Right hepatic lobectomy Case report |
| url | http://link.springer.com/article/10.1186/s12893-020-00742-7 |
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