Bioactive Molecules from Extreme Environments
Marine organisms inhabiting extreme habitats are a promising reservoir of bioactive compounds for drug discovery. Extreme environments, i.e., polar and hot regions, deep sea, hydrothermal vents, marine areas of high pressure or high salinity, experience conditions close to the limit of life. In thes...
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Format: | Article |
Language: | English |
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MDPI AG
2020-12-01
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Series: | Marine Drugs |
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Online Access: | https://www.mdpi.com/1660-3397/18/12/640 |
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author | Daniela Giordano |
author_facet | Daniela Giordano |
author_sort | Daniela Giordano |
collection | DOAJ |
description | Marine organisms inhabiting extreme habitats are a promising reservoir of bioactive compounds for drug discovery. Extreme environments, i.e., polar and hot regions, deep sea, hydrothermal vents, marine areas of high pressure or high salinity, experience conditions close to the limit of life. In these marine ecosystems, “hot spots” of biodiversity, organisms have adopted a huge variety of strategies to cope with such harsh conditions, such as the production of bioactive molecules potentially valuable for biotechnological applications and for pharmaceutical, nutraceutical and cosmeceutical sectors. Many enzymes isolated from extreme environments may be of great interest in the detergent, textile, paper and food industries. Marine natural products produced by organisms evolved under hostile conditions exhibit a wide structural diversity and biological activities. In fact, they exert antimicrobial, anticancer, antioxidant and anti-inflammatory activities. The aim of this Special Issue “Bioactive Molecules from Extreme Environments” was to provide the most recent findings on bioactive molecules as well as enzymes isolated from extreme environments, to be used in biotechnological discovery pipelines and pharmaceutical applications, in an effort to encourage further research in these extreme habitats. |
first_indexed | 2024-03-10T14:04:59Z |
format | Article |
id | doaj.art-84ff9a6179ba45a1a5e7b3f17e835db5 |
institution | Directory Open Access Journal |
issn | 1660-3397 |
language | English |
last_indexed | 2024-03-10T14:04:59Z |
publishDate | 2020-12-01 |
publisher | MDPI AG |
record_format | Article |
series | Marine Drugs |
spelling | doaj.art-84ff9a6179ba45a1a5e7b3f17e835db52023-11-21T00:47:14ZengMDPI AGMarine Drugs1660-33972020-12-01181264010.3390/md18120640Bioactive Molecules from Extreme EnvironmentsDaniela Giordano0Institute of Biosciences and BioResources (IBBR), CNR, Via Pietro Castellino 111, 80131 Napoli, ItalyMarine organisms inhabiting extreme habitats are a promising reservoir of bioactive compounds for drug discovery. Extreme environments, i.e., polar and hot regions, deep sea, hydrothermal vents, marine areas of high pressure or high salinity, experience conditions close to the limit of life. In these marine ecosystems, “hot spots” of biodiversity, organisms have adopted a huge variety of strategies to cope with such harsh conditions, such as the production of bioactive molecules potentially valuable for biotechnological applications and for pharmaceutical, nutraceutical and cosmeceutical sectors. Many enzymes isolated from extreme environments may be of great interest in the detergent, textile, paper and food industries. Marine natural products produced by organisms evolved under hostile conditions exhibit a wide structural diversity and biological activities. In fact, they exert antimicrobial, anticancer, antioxidant and anti-inflammatory activities. The aim of this Special Issue “Bioactive Molecules from Extreme Environments” was to provide the most recent findings on bioactive molecules as well as enzymes isolated from extreme environments, to be used in biotechnological discovery pipelines and pharmaceutical applications, in an effort to encourage further research in these extreme habitats.https://www.mdpi.com/1660-3397/18/12/640Arctic/Antarcticdeep-seadeep hypersaline anoxic basincold-adapted bacteriahalophilic microorganismsmarine natural product |
spellingShingle | Daniela Giordano Bioactive Molecules from Extreme Environments Marine Drugs Arctic/Antarctic deep-sea deep hypersaline anoxic basin cold-adapted bacteria halophilic microorganisms marine natural product |
title | Bioactive Molecules from Extreme Environments |
title_full | Bioactive Molecules from Extreme Environments |
title_fullStr | Bioactive Molecules from Extreme Environments |
title_full_unstemmed | Bioactive Molecules from Extreme Environments |
title_short | Bioactive Molecules from Extreme Environments |
title_sort | bioactive molecules from extreme environments |
topic | Arctic/Antarctic deep-sea deep hypersaline anoxic basin cold-adapted bacteria halophilic microorganisms marine natural product |
url | https://www.mdpi.com/1660-3397/18/12/640 |
work_keys_str_mv | AT danielagiordano bioactivemoleculesfromextremeenvironments |