Bioactive Molecules from Extreme Environments

Marine organisms inhabiting extreme habitats are a promising reservoir of bioactive compounds for drug discovery. Extreme environments, i.e., polar and hot regions, deep sea, hydrothermal vents, marine areas of high pressure or high salinity, experience conditions close to the limit of life. In thes...

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Main Author: Daniela Giordano
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/18/12/640
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author Daniela Giordano
author_facet Daniela Giordano
author_sort Daniela Giordano
collection DOAJ
description Marine organisms inhabiting extreme habitats are a promising reservoir of bioactive compounds for drug discovery. Extreme environments, i.e., polar and hot regions, deep sea, hydrothermal vents, marine areas of high pressure or high salinity, experience conditions close to the limit of life. In these marine ecosystems, “hot spots” of biodiversity, organisms have adopted a huge variety of strategies to cope with such harsh conditions, such as the production of bioactive molecules potentially valuable for biotechnological applications and for pharmaceutical, nutraceutical and cosmeceutical sectors. Many enzymes isolated from extreme environments may be of great interest in the detergent, textile, paper and food industries. Marine natural products produced by organisms evolved under hostile conditions exhibit a wide structural diversity and biological activities. In fact, they exert antimicrobial, anticancer, antioxidant and anti-inflammatory activities. The aim of this Special Issue “Bioactive Molecules from Extreme Environments” was to provide the most recent findings on bioactive molecules as well as enzymes isolated from extreme environments, to be used in biotechnological discovery pipelines and pharmaceutical applications, in an effort to encourage further research in these extreme habitats.
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spelling doaj.art-84ff9a6179ba45a1a5e7b3f17e835db52023-11-21T00:47:14ZengMDPI AGMarine Drugs1660-33972020-12-01181264010.3390/md18120640Bioactive Molecules from Extreme EnvironmentsDaniela Giordano0Institute of Biosciences and BioResources (IBBR), CNR, Via Pietro Castellino 111, 80131 Napoli, ItalyMarine organisms inhabiting extreme habitats are a promising reservoir of bioactive compounds for drug discovery. Extreme environments, i.e., polar and hot regions, deep sea, hydrothermal vents, marine areas of high pressure or high salinity, experience conditions close to the limit of life. In these marine ecosystems, “hot spots” of biodiversity, organisms have adopted a huge variety of strategies to cope with such harsh conditions, such as the production of bioactive molecules potentially valuable for biotechnological applications and for pharmaceutical, nutraceutical and cosmeceutical sectors. Many enzymes isolated from extreme environments may be of great interest in the detergent, textile, paper and food industries. Marine natural products produced by organisms evolved under hostile conditions exhibit a wide structural diversity and biological activities. In fact, they exert antimicrobial, anticancer, antioxidant and anti-inflammatory activities. The aim of this Special Issue “Bioactive Molecules from Extreme Environments” was to provide the most recent findings on bioactive molecules as well as enzymes isolated from extreme environments, to be used in biotechnological discovery pipelines and pharmaceutical applications, in an effort to encourage further research in these extreme habitats.https://www.mdpi.com/1660-3397/18/12/640Arctic/Antarcticdeep-seadeep hypersaline anoxic basincold-adapted bacteriahalophilic microorganismsmarine natural product
spellingShingle Daniela Giordano
Bioactive Molecules from Extreme Environments
Marine Drugs
Arctic/Antarctic
deep-sea
deep hypersaline anoxic basin
cold-adapted bacteria
halophilic microorganisms
marine natural product
title Bioactive Molecules from Extreme Environments
title_full Bioactive Molecules from Extreme Environments
title_fullStr Bioactive Molecules from Extreme Environments
title_full_unstemmed Bioactive Molecules from Extreme Environments
title_short Bioactive Molecules from Extreme Environments
title_sort bioactive molecules from extreme environments
topic Arctic/Antarctic
deep-sea
deep hypersaline anoxic basin
cold-adapted bacteria
halophilic microorganisms
marine natural product
url https://www.mdpi.com/1660-3397/18/12/640
work_keys_str_mv AT danielagiordano bioactivemoleculesfromextremeenvironments