NK cell receptor/H2-Dk-dependent host resistance to viral infection is quantitatively modulated by H2q inhibitory signals.
The cytomegalovirus resistance locus Cmv3 has been linked to an epistatic interaction between two loci: a Natural Killer (NK) cell receptor gene and the major histocompatibility complex class I (MHC-I) locus. To demonstrate the interaction between Cmv3 and H2(k), we generated double congenic mice be...
Main Authors: | Nassima Fodil-Cornu, J Concepción Loredo-Osti, Silvia M Vidal |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-04-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3080855?pdf=render |
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