Metabolomic profiling identifies biomarkers and metabolic impacts of surgery for colorectal cancer

Metabolomic profiling identifies biomarkers and metabolic impacts of surgery for colorectal cancer

BackgroundColorectal cancer (CRC) is one of the most common malignant tumors with recurrence and metastasis after surgical resection. This study aimed to identify the physiological changes after surgery and explore metabolites and metabolic pathways with potential prognostic value for CRC.MethodsAn...

Full description

Bibliographic Details
Main Authors:	Feng Zhuang, Xuesong Bai, Yang Shi, Le Chang, Wanchao Ai, Juan Du, Wei Liu, Humin Liu, Xukun Zhou, Zhong Wang, Tao Hong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Surgery
Subjects:	colorectal cancer metabolomic profiling tumorectomy gamma-linolenic acid (GLA) proline ascorbate
Online Access:	https://www.frontiersin.org/articles/10.3389/fsurg.2022.913967/full

Similar Items

Untargeted Metabolomics and Polyamine Profiling in Serum before and after Surgery in Colorectal Cancer Patients
by: Yu Ra Lee, et al.
Published: (2020-11-01)

Lymphangiome kystique orbitaire envahissant le globe oculaire: à propos d'un cas
by: Wafa Ammari, et al.
Published: (2015-07-01)

Tumores testiculares en la edad pediátrica: indicaciones de la cirugía conservadora
by: Martha Isabel Romo Muñoz, et al.
Published: (2018-05-01)

A quantitative multimodal metabolomic assay for colorectal cancer
by: Farshad Farshidfar, et al.
Published: (2018-01-01)

Untargeted Metabolomics Reveals Major Differences in the Plasma Metabolome between Colorectal Cancer and Colorectal Adenomas
by: Tanja Gumpenberger, et al.
Published: (2021-02-01)

Leiomyosarcoma of the Penis, an Exceptional Entity
by: Edwin Javier Romero Gonzalez, et al.
Published: (2015-05-01)

Extrahepatic Vitamin K-Dependent Gla-Proteins–Potential Cardiometabolic Biomarkers
by: Bistra Galunska, et al.
Published: (2024-03-01)

A Fecal-Microbial-Extracellular-Vesicles-Based Metabolomics Machine Learning Framework and Biomarker Discovery for Predicting Colorectal Cancer Patients
by: Fatma Hilal Yagin, et al.
Published: (2023-04-01)

Genomic and Metabolomic Landscape of Right-Sided and Left-Sided Colorectal Cancer: Potential Preventive Biomarkers
by: Ming-Wei Su, et al.
Published: (2022-02-01)

Comprehensive Analysis of Metabolome and Transcriptome Reveals the Regulatory Network of Coconut Nutrients
by: Hao Guo, et al.
Published: (2023-05-01)

Orthotopic model for the analysis of melanoma circulating tumor cells
by: Markéta Pícková, et al.
Published: (2024-04-01)

Influence of unsaturated fatty acids on the antitumor activity of polymeric conjugates grafted with cabazitaxel against prostate cancer
by: Hongshuai Lv, et al.
Published: (2023-12-01)

Metabolomic Biomarkers for Detection, Prognosis and Identifying Recurrence in Endometrial Cancer
by: Kelechi Njoku, et al.
Published: (2020-07-01)

Alleviating Air Pollutants Impact by Some Chemicals and Planting Distance off the Freeway and Their Effect on Pears Productivity and Fruit Quality
by: Ahmed El-Shiekh, et al.
Published: (2023-01-01)

Metabolomics tools for identifying biomarkers for neuropsychiatric diseases
by: Marlon P. Quinones, et al.
Published: (2009-08-01)

Biomanufacturing of γ-linolenic acid-enriched galactosyldiacylglycerols: Challenges in microalgae and potential in oleaginous yeasts
by: Xiaosong Gu, et al.
Published: (2023-09-01)

1H-NMR Based Metabolomics Technology Identifies Potential Serum Biomarkers of Colorectal Cancer Lung Metastasis in a Mouse Model
by: Zhang J, et al.
Published: (2022-04-01)

The effect of consuming evening primrose oil on cervical preparation before hysteroscopy: An RCT
by: Mandana Mansour Ghanaei, et al.
Published: (2022-07-01)

Matrix Gla Protein – a new marker for colorectal cancer detection? A systematic review
by: Mirela-Georgiana Perné, et al.
Published: (2023-04-01)

Data on the evaluation of FGF2 gene expression in Colorectal Cancer
by: Helena Caiado, et al.
Published: (2020-08-01)

Multiplatform Urinary Metabolomics Profiling to Discriminate Cachectic from Non-Cachectic Colorectal Cancer Patients: Pilot Results from the ColoCare Study
by: Jennifer Ose, et al.
Published: (2019-09-01)

Manipulation of Alcohol and Short-Chain Fatty Acids in the Metabolome of Commensal and Virulent <em>Klebsiella pneumoniae</em> by Linolenic Acid
by: Ryan Yuki Huang, et al.
Published: (2020-05-01)

Morphological and Physiological Responses of In Vitro-Grown <i>Cucurbita</i> sp. Landraces Seedlings under Osmotic Stress by Mannitol and PEG
by: Rana Panahi Tajaragh, et al.
Published: (2022-11-01)

Metabolomics Biomarkers for Detection of Colorectal Neoplasms: A Systematic Review
by: Vanessa Erben, et al.
Published: (2018-07-01)

Fecal Metabolomic Signatures in Colorectal Adenoma Patients Are Associated with Gut Microbiota and Early Events of Colorectal Cancer Pathogenesis
by: Minsuk Kim, et al.
Published: (2020-02-01)

Global metabolomics profiling of colorectal cancer in Malaysian patients
by: Nurul Azmir Amir Hashim, et al.
Published: (2021-01-01)

The Distinctive Serum Metabolomes of Gastric, Esophageal and Colorectal Cancers
by: Zhenxing Ren, et al.
Published: (2021-02-01)

Integration of the Microbiome, Metabolome and Transcriptomics Data Identified Novel Metabolic Pathway Regulation in Colorectal Cancer
by: Vartika Bisht, et al.
Published: (2021-05-01)

Association of Dietary Intake and Biomarker of α-Linolenic Acid With Incident Colorectal Cancer: A Dose-Response Meta-Analysis of Prospective Cohort Studies
by: Ze-Bin Dai, et al.
Published: (2022-07-01)

Effects of dietary gamma-linolenic acid and docosahexaenoic acid with paclitaxel on the treatment of mice mammary carcinoma
by: Kamran Rakhshan, et al.
Published: (2013-08-01)

γ-Linolenic Acid versus α-Lipoic Acid for Treating Painful Diabetic Neuropathy in Adults: A 12-Week, Double-Placebo, Randomized, Noninferiority Trial
by: Jong Chul Won, et al.
Published: (2020-08-01)

Infantile hepatic hemangioma and hepatic mesenchymal hamartoma in an infant associated with placental mesenchymal dysplasia: a case report
by: Shunsuke Fujii, et al.
Published: (2022-08-01)

Rectosigmoid sparing en bloc pelvic resection for fixed ovarian tumors: Surgical technique and perioperative and oncologic outcomes
by: Ying Shan, et al.
Published: (2022-08-01)

Interplay between Genome, Metabolome and Microbiome in Colorectal Cancer
by: Koldo Garcia-Etxebarria, et al.
Published: (2021-12-01)

A Metabolomic Signature of Obesity and Risk of Colorectal Cancer: Two Nested Case–Control Studies
by: Mingjia Yang, et al.
Published: (2023-02-01)

<i>Zat12</i> Gene Ameliorates Temperature Stress in Wheat Transgenics by Modulating the Antioxidant Defense System
by: Manpreet Kaur, et al.
Published: (2023-02-01)

Oxidative Damage and Antioxidant Response in Chenopodium murale L. Exposed to Elevated Levels of Zn
by: Parzhak Zoufan, et al.
Published: (2018-10-01)

Response of chickpea (Cicer arietinum L.) to exogenous salicylic acid and ascorbic acid under vegetative and reproductive drought stress conditions
by: Asad Rokhzadi
Published: (2014-04-01)

Global Responses of Autopolyploid Sugarcane Badila (<i>Saccharum officinarum</i> L.) to Drought Stress Based on Comparative Transcriptome and Metabolome Profiling
by: Shan Yang, et al.
Published: (2023-02-01)

Integrative analysis of the mouse fecal microbiome and metabolome reveal dynamic phenotypes in the development of colorectal cancer
by: Jingjing Liu, et al.
Published: (2022-09-01)