Comparison of Point of Care (POC) Testing of Glucose by B Braun Glucometer and Hemocue Glucose 201+ Analyser Versus Centralised Testing in Neonatal Intensive Care Unit (NICU)
Background: Neonatal hypoglycemia is the most common carbohydrate metabolic disturbance seen in case of neonates and especially in preterm neonates. Accurate and rapid determination of hypoglycemia and its prompt treatment is of utmost importance to decrease morbidity and mortality of neonates....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2014-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/4538/8666_CE[Ra1]_F(DK)_PF1(PAK)_PFA(AK)_PF2(AGAK).pdf |
| Summary: | Background: Neonatal hypoglycemia is the most common
carbohydrate metabolic disturbance seen in case of neonates and
especially in preterm neonates. Accurate and rapid determination
of hypoglycemia and its prompt treatment is of utmost importance
to decrease morbidity and mortality of neonates.
Aims: To estimate blood glucose in neonates and test the efficacy
of HemoCue Glucose 201+ analyser and B Braun Glucometer
by comparing with centralised laboratory testing. To compare
the blood glucose in capillary and venous blood samples of
neonates.
Settings and Design: Hospital setting; Comparative Study
Materials and Methods: After obtaining informed consent, all
neonates admitted to Neonatal Intensive Care Unit (NICU) were
screened for blood sugar. Capillary and venous blood glucose
was estimated employing HemoCue Glucose 201+ analyser
and B Braun Glucometer. Simultaneously, the same venous
sample was collected in fluoride tube and sent to central clinical
biochemistry laboratory for glucose estimation. When anaemia or
polycythemia was clinically suspected the same venous sample
was sent for estimation of Hematocrit (Hct).
Statistical Analysis: Comparison of blood glucose concentration
of B Braun glucometer, HemoCue Glucose 201+ analyser and
centralis/ed plasma glucose levels was done by using students
test. All the statistical analysis were done using software SPSS
6 version.
Results: Mean values of blood glucose (100.2 + 48.4) with B
Braun glucometer was significantly higher (p=0.003) when
compared to plasma glucose values (76.95 + 45.99) estimated in
central laboratory and HemoCue glucose 201+ analyser (82.9 +
51.4). HemoCue glucose 201+ analyser did not show significant
difference (p=0.463) with central laboratory testing. There was no
significant difference between the capillary and venous sample
estimated in both the instruments. Estimation with HemoCue
glucose 201+ analyser correlated well with central laboratory
testing in neonates with blood glucose <55mg/dl,
Conclusion: We conclude that HemoCue glucose 201+ analyser
appears to be a suitable point of care (POC) blood glucose
measurement device in neonates on both capillary and venous
blood samples, as it showed a good correlation with central
laboratory values without significant interference from Hct. |
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| ISSN: | 2249-782X 0973-709X |