Emodin ameliorates renal injury and fibrosis via regulating the miR-490-3p/HMGA2 axis

Emodin ameliorates renal injury and fibrosis via regulating the miR-490-3p/HMGA2 axis

Renal fibrosis is a major pathological feature of chronic kidney disease (CKD). While emodin is reported to elicit anti-fibrotic effects on renal injury, little is known about its effects on microRNA (miRNA)-modulated mechanisms in renal fibrosis. In this study, we established a unilateral ureteral...

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Bibliographic Details
Main Authors: Liulin Wang, Xuerui Wang, Gang Li, Shanshan Zhou, Rui Wang, Qi Long, Min Wang, Liang Li, Hai Huang, Yuanming Ba
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
emodin
renal fibrosis
microRNA
inflammatory factor
HMGA2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1042093/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1042093/full

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