Global circRNA expression changes predate clinical and histological improvements of psoriasis patients upon secukinumab treatment.

Global circRNA expression changes predate clinical and histological improvements of psoriasis patients upon secukinumab treatment.

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Psoriasis is a common chronic inflammatory skin disease accompanied by heterogenous clinical and histological features, including a characteristic keratinocyte hyperproliferation and dermal immunogenic profile. In addition, psoriasis is associated with widespread transcriptomic alterations including...

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Bibliographic Details
Main Authors: Sabine Seeler, Liviu-Ionut Moldovan, Trine Bertelsen, Henrik Hager, Lars Iversen, Claus Johansen, Jørgen Kjems, Lasse Sommer Kristensen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0275219

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