COVID-19 in Cyanotic Congenital Heart Disease

Congenital heart disease (CHD) is the most prevalent congenital defect in newborn infants. Due to the various types of heart abnormalities, CHD can have a wide range of symptoms. Cardiac lesions comprise a range of different types and accordingly varying severities. It is highly helpful to classify...

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Main Authors: Lama A Ammar, Joseph E Nassar, Fadi Bitar, Mariam Arabi
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2023/5561159
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author Lama A Ammar
Joseph E Nassar
Fadi Bitar
Mariam Arabi
author_facet Lama A Ammar
Joseph E Nassar
Fadi Bitar
Mariam Arabi
author_sort Lama A Ammar
collection DOAJ
description Congenital heart disease (CHD) is the most prevalent congenital defect in newborn infants. Due to the various types of heart abnormalities, CHD can have a wide range of symptoms. Cardiac lesions comprise a range of different types and accordingly varying severities. It is highly helpful to classify CHD into cyanotic and acyanotic heart diseases. In this review, we are investigating the course of Coronavirus disease 2019 (COVID-19) in cyanotic CHD patients. The infection may directly or indirectly affect the heart by affecting the respiratory system and other organs. The effect on the heart that is pressure- or volume-overloaded in the context of CHD is theoretically more severe. Patients with CHD are at a higher risk of mortality from COVID-19 infection or suffering worse complications. While the anatomic complexity of CHD does not seem to predict the severity of infection, patients with worse physiological stages are more susceptible such as cyanosis and pulmonary hypertension. Patients with CHD exhibit continuous hypoxemia and have lower oxygen saturations because of a right-to-left shunt. Such individuals run the danger of rapidly deteriorating in the event of respiratory tract infections with inadequate oxygenation. Additionally, these patients have a higher risk of paradoxical embolism. Hence, critical care should be given to cyanotic heart disease patients with COVID-19 in comparison to acyanotic patients and this is through proper management, close observation, and adequate medical therapy.
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spelling doaj.art-850b498d7bfd4ba3a497ae56c1c66b792023-04-26T00:00:06ZengHindawi LimitedCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932023-01-01202310.1155/2023/5561159COVID-19 in Cyanotic Congenital Heart DiseaseLama A Ammar0Joseph E Nassar1Fadi Bitar2Mariam Arabi3Faculty of Medicine and Medical CenterFaculty of Medicine and Medical CenterFaculty of Medicine and Medical CenterFaculty of Medicine and Medical CenterCongenital heart disease (CHD) is the most prevalent congenital defect in newborn infants. Due to the various types of heart abnormalities, CHD can have a wide range of symptoms. Cardiac lesions comprise a range of different types and accordingly varying severities. It is highly helpful to classify CHD into cyanotic and acyanotic heart diseases. In this review, we are investigating the course of Coronavirus disease 2019 (COVID-19) in cyanotic CHD patients. The infection may directly or indirectly affect the heart by affecting the respiratory system and other organs. The effect on the heart that is pressure- or volume-overloaded in the context of CHD is theoretically more severe. Patients with CHD are at a higher risk of mortality from COVID-19 infection or suffering worse complications. While the anatomic complexity of CHD does not seem to predict the severity of infection, patients with worse physiological stages are more susceptible such as cyanosis and pulmonary hypertension. Patients with CHD exhibit continuous hypoxemia and have lower oxygen saturations because of a right-to-left shunt. Such individuals run the danger of rapidly deteriorating in the event of respiratory tract infections with inadequate oxygenation. Additionally, these patients have a higher risk of paradoxical embolism. Hence, critical care should be given to cyanotic heart disease patients with COVID-19 in comparison to acyanotic patients and this is through proper management, close observation, and adequate medical therapy.http://dx.doi.org/10.1155/2023/5561159
spellingShingle Lama A Ammar
Joseph E Nassar
Fadi Bitar
Mariam Arabi
COVID-19 in Cyanotic Congenital Heart Disease
Canadian Journal of Infectious Diseases and Medical Microbiology
title COVID-19 in Cyanotic Congenital Heart Disease
title_full COVID-19 in Cyanotic Congenital Heart Disease
title_fullStr COVID-19 in Cyanotic Congenital Heart Disease
title_full_unstemmed COVID-19 in Cyanotic Congenital Heart Disease
title_short COVID-19 in Cyanotic Congenital Heart Disease
title_sort covid 19 in cyanotic congenital heart disease
url http://dx.doi.org/10.1155/2023/5561159
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AT josephenassar covid19incyanoticcongenitalheartdisease
AT fadibitar covid19incyanoticcongenitalheartdisease
AT mariamarabi covid19incyanoticcongenitalheartdisease