A systematic review and meta-analysis of the diagnostic accuracy of metagenomic next-generation sequencing for diagnosing tuberculous meningitis

A systematic review and meta-analysis of the diagnostic accuracy of metagenomic next-generation sequencing for diagnosing tuberculous meningitis

ObjectiveThe utility of metagenomic next-generation sequencing (mNGS) in the diagnosis of tuberculous meningitis (TBM) remains uncertain. We performed a meta-analysis to comprehensively evaluate its diagnostic accuracy for the early diagnosis of TBM.MethodsEnglish (PubMed, Medline, Web of Science, C...

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Bibliographic Details
Main Authors: Zheng-Bing Xiang, Er-Ling Leng, Wen-Feng Cao, Shi-Min Liu, Yong-Liang Zhou, Chao-Qun Luo, Fan Hu, An Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
tuberculous meningitis
cerebrospinal fluid
metagenomic next-generation sequencing
diagnosis
meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1223675/full

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