Anti-Inflammatory Effects of 5α,8α-Epidioxycholest-6-en-3β-ol, a Steroidal Endoperoxide Isolated from <i>Aplysia depilans</i>, Based on Bioguided Fractionation and NMR Analysis

Anti-Inflammatory Effects of 5α,8α-Epidioxycholest-6-en-3β-ol, a Steroidal Endoperoxide Isolated from <i>Aplysia depilans</i>, Based on Bioguided Fractionation and NMR Analysis

Sea hares of <i>Aplysia</i> genus are recognized as a source of a diverse range of metabolites. 5&#945;,8&#945;-Endoperoxides belong to a group of oxidized sterols commonly found in marine organisms and display several bioactivities, including antimicrobial, anti-tumor, and immun...

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Bibliographic Details
Main Authors: Renato B. Pereira, David M. Pereira, Carlos Jiménez, Jaime Rodríguez, Rosa M. Nieto, Romeu A. Videira, Olga Silva, Paula B. Andrade, Patrícia Valentão
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Marine Drugs
Subjects:
<i>Aplysia depilans</i>
5α,8α-epidioxycholest-6-en-3β-ol
iNOS
COX-1
COX-2
IL-6
TNF-α
Online Access:https://www.mdpi.com/1660-3397/17/6/330

Internet

https://www.mdpi.com/1660-3397/17/6/330

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