A Step-by-Step Refined Strategy for Highly Efficient Generation of Neural Progenitors and Motor Neurons from Human Pluripotent Stem Cells

A Step-by-Step Refined Strategy for Highly Efficient Generation of Neural Progenitors and Motor Neurons from Human Pluripotent Stem Cells

Limited access to human neurons, especially motor neurons (MNs), was a major challenge for studying neurobiology and neurological diseases. Human pluripotent stem cells (hPSCs) could be induced as neural progenitor cells (NPCs) and further multiple neural subtypes, which provide excellent cellular s...

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Bibliographic Details
Main Authors: Jie Ren, Chaoyi Li, Mengfei Zhang, Huakun Wang, Yali Xie, Yu Tang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
pluripotent stem cells
neural progenitor cells
neural differentiation
RA
SMAD
motor neuron
Online Access:https://www.mdpi.com/2073-4409/10/11/3087

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