Inflammatory markers in rheumatic diseases
Immune-mediated rheumatic diseases (IMRDs) are a broad group of pathological conditions based on impaired immunological tolerance to one’s own tissues leading to inflammation and irreversible organ damage. Laboratory diagnosis of IMRDs includes a wide range of biomarkers (autoantibodies, acute phase...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2022-12-01
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| Series: | Научно-практическая ревматология |
| Subjects: | |
| Online Access: | https://rsp.mediar-press.net/rsp/article/view/3245 |
| _version_ | 1797862588819701760 |
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| author | A. S. Avdeeva |
| author_facet | A. S. Avdeeva |
| author_sort | A. S. Avdeeva |
| collection | DOAJ |
| description | Immune-mediated rheumatic diseases (IMRDs) are a broad group of pathological conditions based on impaired immunological tolerance to one’s own tissues leading to inflammation and irreversible organ damage. Laboratory diagnosis of IMRDs includes a wide range of biomarkers (autoantibodies, acute phase proteins, cytokines, markers of endothelial damage, components of the complement system, immunoglobulins, cryoglobulins, lymphocyte subpopulations, indicators of bone metabolism, apoptosis markers, genetic markers, etc). One of the leading aspects of laboratory diagnosis of IMRDs is the study of the level of inflammation markers in the blood (erythrocyte sedimentation rate, C-reactive protein (CRP), serum amyloid protein (CAA), ferritin, procalcitonin, apolipoprotein AI, calprotectin, etc). The analysis of inflammation markers makes it possible to assess the disease activity, the nature of the progression and the prognosis of the outcomes of a chronic inflammatory process, as well as the effectiveness of the therapy. The review presents the latest data on the role of the most frequently studied inflammatory markers such as CRP, CAA and ferritin. |
| first_indexed | 2024-04-09T22:21:47Z |
| format | Article |
| id | doaj.art-851afad57f0a41c7bafbf326402b8627 |
| institution | Directory Open Access Journal |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| last_indexed | 2024-04-09T22:21:47Z |
| publishDate | 2022-12-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj.art-851afad57f0a41c7bafbf326402b86272023-03-22T13:45:58ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922022-12-0160610.47360/1995-4484-2022-561-5692858Inflammatory markers in rheumatic diseasesA. S. Avdeeva0V.A. Nasonova Research Institute of RheumatologyImmune-mediated rheumatic diseases (IMRDs) are a broad group of pathological conditions based on impaired immunological tolerance to one’s own tissues leading to inflammation and irreversible organ damage. Laboratory diagnosis of IMRDs includes a wide range of biomarkers (autoantibodies, acute phase proteins, cytokines, markers of endothelial damage, components of the complement system, immunoglobulins, cryoglobulins, lymphocyte subpopulations, indicators of bone metabolism, apoptosis markers, genetic markers, etc). One of the leading aspects of laboratory diagnosis of IMRDs is the study of the level of inflammation markers in the blood (erythrocyte sedimentation rate, C-reactive protein (CRP), serum amyloid protein (CAA), ferritin, procalcitonin, apolipoprotein AI, calprotectin, etc). The analysis of inflammation markers makes it possible to assess the disease activity, the nature of the progression and the prognosis of the outcomes of a chronic inflammatory process, as well as the effectiveness of the therapy. The review presents the latest data on the role of the most frequently studied inflammatory markers such as CRP, CAA and ferritin.https://rsp.mediar-press.net/rsp/article/view/3245immune-mediated rheumatic diseasesinflammatory markersc-reactive proteinserum amyloid protein aferritin |
| spellingShingle | A. S. Avdeeva Inflammatory markers in rheumatic diseases Научно-практическая ревматология immune-mediated rheumatic diseases inflammatory markers c-reactive protein serum amyloid protein a ferritin |
| title | Inflammatory markers in rheumatic diseases |
| title_full | Inflammatory markers in rheumatic diseases |
| title_fullStr | Inflammatory markers in rheumatic diseases |
| title_full_unstemmed | Inflammatory markers in rheumatic diseases |
| title_short | Inflammatory markers in rheumatic diseases |
| title_sort | inflammatory markers in rheumatic diseases |
| topic | immune-mediated rheumatic diseases inflammatory markers c-reactive protein serum amyloid protein a ferritin |
| url | https://rsp.mediar-press.net/rsp/article/view/3245 |
| work_keys_str_mv | AT asavdeeva inflammatorymarkersinrheumaticdiseases |