Olopatadine Inhibits Exocytosis in Rat Peritoneal Mast Cells by Counteracting Membrane Surface Deformation

Olopatadine Inhibits Exocytosis in Rat Peritoneal Mast Cells by Counteracting Membrane Surface Deformation

Backgroud/Aims: Besides its anti-allergic properties as a histamine receptor antagonist, olopatadine stabilizes mast cells by inhibiting the release of chemokines. Since olopatadine bears amphiphilic features and is preferentially partitioned into the lipid bilayers of the plasma membrane, it would...

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Bibliographic Details
Main Authors:	Asuka Baba, Masahiro Tachi, Yoshio Maruyama, Itsuro Kazama
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Olopatadine Mast cell stabilizing properties Rat peritoneal mast cells Exocytosis Membrane capacitance Plasma membrane deformation
Online Access:	http://www.karger.com/Article/FullText/369704

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