The principles of experimental traumatic brain injury modelling

The contemporary approaches to traumatic brain injury modeling, the principles of functioning and technical characteristics of appropriate equipment are reviewed. The methods describing traumatic brain injury modeling and assessment of brain structural and functional changes caused by tra...

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Main Author: V. V. Biloshytsky
Format: Article
Language:English
Published: Romodanov Neurosurgery Institute 2008-12-01
Series:Ukrainian Neurosurgical Journal
Online Access:https://theunj.org/article/view/108232
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author V. V. Biloshytsky
author_facet V. V. Biloshytsky
author_sort V. V. Biloshytsky
collection DOAJ
description The contemporary approaches to traumatic brain injury modeling, the principles of functioning and technical characteristics of appropriate equipment are reviewed. The methods describing traumatic brain injury modeling and assessment of brain structural and functional changes caused by trauma are given. Author suggested the combined use of: 1) histological investigation including quantitative estimation of hippocampal pyramidal neurons; 2) assessment of motor dysfunction; 3) assessment of cognitive dysfunction, as reliable morphological and neurological criteria of experimental brain injury severity and therapy efficacy. The information regarding the traumatic brain injury modeling contained in original scientific reports and reviews of literature are analyzed.
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spelling doaj.art-852449336f0d47559cb42919f93f2fd62024-02-03T08:07:45ZengRomodanov Neurosurgery InstituteUkrainian Neurosurgical Journal2663-90842663-90922008-12-01491510.25305/unj.108232The principles of experimental traumatic brain injury modellingV. V. Biloshytsky0Romodanov Neurosurgery Institute, Kiev, Ukraine The contemporary approaches to traumatic brain injury modeling, the principles of functioning and technical characteristics of appropriate equipment are reviewed. The methods describing traumatic brain injury modeling and assessment of brain structural and functional changes caused by trauma are given. Author suggested the combined use of: 1) histological investigation including quantitative estimation of hippocampal pyramidal neurons; 2) assessment of motor dysfunction; 3) assessment of cognitive dysfunction, as reliable morphological and neurological criteria of experimental brain injury severity and therapy efficacy. The information regarding the traumatic brain injury modeling contained in original scientific reports and reviews of literature are analyzed.https://theunj.org/article/view/108232
spellingShingle V. V. Biloshytsky
The principles of experimental traumatic brain injury modelling
Ukrainian Neurosurgical Journal
title The principles of experimental traumatic brain injury modelling
title_full The principles of experimental traumatic brain injury modelling
title_fullStr The principles of experimental traumatic brain injury modelling
title_full_unstemmed The principles of experimental traumatic brain injury modelling
title_short The principles of experimental traumatic brain injury modelling
title_sort principles of experimental traumatic brain injury modelling
url https://theunj.org/article/view/108232
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