Treatment outcomes of tuberculosis among new smear-positive and retreatment cases: a retrospective study in two Egyptian governorates

Background Tuberculosis (TB) affects millions of people every year and is considered one of the top 10 causes of death worldwide, being more than HIV/AIDS. Objective The objective of this study was to investigate the effect of directly observed treatment–short course on treatment outcomes among new...

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Main Authors: Fawzy El Emeiry, Safynaz Shalaby, Gehan H Abo El-Magd, Marwa Madi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Egyptian Journal of Chest Disease and Tuberculosis
Subjects:
Online Access:http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2019;volume=68;issue=3;spage=274;epage=283;aulast=El
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author Fawzy El Emeiry
Safynaz Shalaby
Gehan H Abo El-Magd
Marwa Madi
author_facet Fawzy El Emeiry
Safynaz Shalaby
Gehan H Abo El-Magd
Marwa Madi
author_sort Fawzy El Emeiry
collection DOAJ
description Background Tuberculosis (TB) affects millions of people every year and is considered one of the top 10 causes of death worldwide, being more than HIV/AIDS. Objective The objective of this study was to investigate the effect of directly observed treatment–short course on treatment outcomes among new smear-positive and retreatment cases of TB in two Egyptian governorates: Gharbia and Menoufia. Patients and methods This retrospective study was carried out on the records obtained from TB Registration Unit in Gharbia and Menoufia governorates. The study included the diagnosed and registered cases of new smear-positive and retreatment cases of TB during the years 2008–2013 in the two governorates. Results The total number of studied TB cases was 916 (669 males and 247 females) and 825 cases (632 males and 193 females) in Gharbia and Menoufia governorates, respectively. TB was common in rural areas compared with urban areas. The highest rate of treatment outcomes was cure rate (85.8 and 88.2% in Gharbia and Menoufia governorates, respectively) with significant decrease of failure (4 and 1.3%), death (3.3 and 1.9%), default (0.8 and 2.1%) and transfer out (1.9 and 1.9%) rates in Gharbia and Menoufia governorates, respectively. The success rates were 825 (90.1%) in Gharbia and 765 (92.7%) in Menoufia governorates. Conclusion Treatment success rates among new smear-positive and retreatment cases were 90.1 and 92.7% in Gharbia and Menoufia governorates, respectively, with low poor outcomes, which in turn indicated high efficacy and successful application of directly observed treatment–short course.
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spelling doaj.art-85263d07723e4904bfd279485ec75d9e2022-12-21T18:20:38ZengWolters Kluwer Medknow PublicationsEgyptian Journal of Chest Disease and Tuberculosis0422-76382090-99502019-01-0168327428310.4103/ejcdt.ejcdt_202_18Treatment outcomes of tuberculosis among new smear-positive and retreatment cases: a retrospective study in two Egyptian governoratesFawzy El EmeirySafynaz ShalabyGehan H Abo El-MagdMarwa MadiBackground Tuberculosis (TB) affects millions of people every year and is considered one of the top 10 causes of death worldwide, being more than HIV/AIDS. Objective The objective of this study was to investigate the effect of directly observed treatment–short course on treatment outcomes among new smear-positive and retreatment cases of TB in two Egyptian governorates: Gharbia and Menoufia. Patients and methods This retrospective study was carried out on the records obtained from TB Registration Unit in Gharbia and Menoufia governorates. The study included the diagnosed and registered cases of new smear-positive and retreatment cases of TB during the years 2008–2013 in the two governorates. Results The total number of studied TB cases was 916 (669 males and 247 females) and 825 cases (632 males and 193 females) in Gharbia and Menoufia governorates, respectively. TB was common in rural areas compared with urban areas. The highest rate of treatment outcomes was cure rate (85.8 and 88.2% in Gharbia and Menoufia governorates, respectively) with significant decrease of failure (4 and 1.3%), death (3.3 and 1.9%), default (0.8 and 2.1%) and transfer out (1.9 and 1.9%) rates in Gharbia and Menoufia governorates, respectively. The success rates were 825 (90.1%) in Gharbia and 765 (92.7%) in Menoufia governorates. Conclusion Treatment success rates among new smear-positive and retreatment cases were 90.1 and 92.7% in Gharbia and Menoufia governorates, respectively, with low poor outcomes, which in turn indicated high efficacy and successful application of directly observed treatment–short course.http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2019;volume=68;issue=3;spage=274;epage=283;aulast=Eldirectly observed treatment–short courseGharbiaMenoufianewpulmonary tuberculosistreatment outcomes
spellingShingle Fawzy El Emeiry
Safynaz Shalaby
Gehan H Abo El-Magd
Marwa Madi
Treatment outcomes of tuberculosis among new smear-positive and retreatment cases: a retrospective study in two Egyptian governorates
Egyptian Journal of Chest Disease and Tuberculosis
directly observed treatment–short course
Gharbia
Menoufia
new
pulmonary tuberculosis
treatment outcomes
title Treatment outcomes of tuberculosis among new smear-positive and retreatment cases: a retrospective study in two Egyptian governorates
title_full Treatment outcomes of tuberculosis among new smear-positive and retreatment cases: a retrospective study in two Egyptian governorates
title_fullStr Treatment outcomes of tuberculosis among new smear-positive and retreatment cases: a retrospective study in two Egyptian governorates
title_full_unstemmed Treatment outcomes of tuberculosis among new smear-positive and retreatment cases: a retrospective study in two Egyptian governorates
title_short Treatment outcomes of tuberculosis among new smear-positive and retreatment cases: a retrospective study in two Egyptian governorates
title_sort treatment outcomes of tuberculosis among new smear positive and retreatment cases a retrospective study in two egyptian governorates
topic directly observed treatment–short course
Gharbia
Menoufia
new
pulmonary tuberculosis
treatment outcomes
url http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2019;volume=68;issue=3;spage=274;epage=283;aulast=El
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