Effect of regulating macrophage polarization phenotype on intervertebral disc degeneration

Effect of regulating macrophage polarization phenotype on intervertebral disc degeneration

Abstract Background Macrophages are the only inflammatory cells that can penetrate the closed nucleus pulposus and their polarization plays an important role in intervertebral disc degeneration (IVDD). This paper attempted to investigate the pathogenesis of IVDD by altering the polarization state of...

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Bibliographic Details
Main Authors: Xuefeng Hou, Yucheng Shen, Minli Sun, Bing Zhang, Jiuming Dai, Dong Chen, Zhidong Liu
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Immunity, Inflammation and Disease
Subjects:
inflammation
intervertebral disc degeneration
M1 polarization
macrophages
Online Access:https://doi.org/10.1002/iid3.714

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