Mini-review: Mitochondrial DNA methylation in type 2 diabetes and obesity

Mini-review: Mitochondrial DNA methylation in type 2 diabetes and obesity

Type 2 diabetes (T2D) and obesity are two of the most challenging public health problems of our time. Therefore, understanding the molecular mechanisms that contribute to these complex metabolic disorders is essential. An underlying pathophysiological condition of T2D and obesity is insulin resistan...

Full description

Bibliographic Details
Main Authors:	Emma K. Rautenberg, Yassin Hamzaoui, Dawn K. Coletta
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Endocrinology
Subjects:	mitochondria epigenetics methylation insulin resistance skeletal muscle obesity
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2022.968268/full

Similar Items

Can Exercise Training Alter Human Skeletal Muscle DNA Methylation?
by: Luis A. Garcia, et al.
Published: (2022-03-01)

Nonequilibrium thermodynamics and mitochondrial protein content predict insulin sensitivity and fuel selection during exercise in human skeletal muscle
by: Rocio Zapata Bustos, et al.
Published: (2023-07-01)

Alterations of sorbin and SH3 domain containing 3 (SORBS3) in human skeletal muscle following Roux-en-Y gastric bypass surgery
by: Samantha E. Day, et al.
Published: (2017-09-01)

Potential epigenetic biomarkers of obesity-related insulin resistance in human whole-blood
by: Samantha E. Day, et al.
Published: (2017-04-01)

Inspiratory muscle strength training to improve cardiometabolic health in patients with type 2 diabetes mellitus: protocol for the diabetes inspiratory training clinical trial
by: Baylee L. Reed, et al.
Published: (2024-09-01)

Altered Transcription Factor Expression Responses to Exercise in Insulin Resistance
by: Rocio Zapata-Bustos, et al.
Published: (2021-04-01)

The potential of DNA methylation markers in the study of obesity
by: A. F. Nikolaeva, et al.
Published: (2024-01-01)

Epigenetics of Mitochondria-Associated Genes in Striated Muscle
by: Kenneth C. Ehrlich, et al.
Published: (2022-12-01)

Mitochondrial Phenotype as a Driver of the Racial Dichotomy in Obesity and Insulin Resistance
by: Filip Jevtovic, et al.
Published: (2022-06-01)

A performance review of novel adiposity indices for assessing insulin resistance in a pediatric Latino population
by: Mac B. McGraw, et al.
Published: (2022-10-01)

Meta‐analysis of genome‐wide DNA methylation and integrative omics of age in human skeletal muscle
by: Sarah Voisin, et al.
Published: (2021-08-01)

Skeletal Muscle Mitochondrial and Perilipin Content in a Cohort of Obese Subjects Undergoing Moderate and High Intensity Training
by: Giuseppe Sirago, et al.
Published: (2022-09-01)

Current Updates on the Understanding of the Role of DNA Methylation on Obesity
by: Lastialno MP, et al.
Published: (2024-08-01)

DNA Methylation Reorganization of Skeletal Muscle-Specific Genes in Response to Gestational Obesity
by: Anna Prats-Puig, et al.
Published: (2020-07-01)

Sex differences in muscle protein expression and DNA methylation in response to exercise training
by: Shanie Landen, et al.
Published: (2023-09-01)

Insights into the development of insulin resistance: Unraveling the interaction of physical inactivity, lipid metabolism and mitochondrial biology
by: Rachel M. Handy, et al.
Published: (2023-04-01)

Methylation of Ribosomal RNA: A Mitochondrial Perspective
by: M. Isabel G. Lopez Sanchez, et al.
Published: (2020-07-01)

The Effects of Glucagon‐Like Peptide‐1 Receptor Agonists on Mitochondrial Function Within Skeletal Muscle: A Systematic Review
by: Victoria J. Old, et al.
Published: (2025-02-01)

DNA methylation of insulin signaling pathways is associated with HOMA2-IR in primary myoblasts from older adults
by: Mark A. Burton, et al.
Published: (2023-10-01)

Evidence Suggesting Absence of Mitochondrial DNA Methylation
by: Mie Mechta, et al.
Published: (2017-11-01)

Dual Regulation Mechanism of Obesity: DNA Methylation and Intestinal Flora
by: Yi Ren, et al.
Published: (2024-07-01)

DNA methylation links genetics, fetal environment, and an unhealthy lifestyle to the development of type 2 diabetes
by: Emma Nilsson, et al.
Published: (2017-10-01)

Exercise and obesity-induced insulin resistance in skeletal muscle
by: Hyo-Bum Kwak
Published: (2013-12-01)

Mitochondrial dysfunction in skeletal muscle contributes to the development of acute insulin resistance in mice
by: Hyunjung Lee, et al.
Published: (2021-12-01)

Local DNA methylation helps to regulate muscle sirtuin 1 gene expression across seasons and advancing age in gilthead sea bream (Sparus aurata)
by: Paula Simó-Mirabet, et al.
Published: (2020-05-01)

HIV-1 Tat and cocaine impact mitochondrial epigenetics: effects on DNA methylation
by: Mayur Doke, et al.
Published: (2021-09-01)

Mitochondrial Properties in Skeletal Muscle Fiber
by: Han Dong, et al.
Published: (2023-08-01)

Melatonin Alleviates the Impairment of Muscle Bioenergetics and Protein Quality Control Systems in Leptin-Deficiency-Induced Obesity
by: Yaiza Potes, et al.
Published: (2023-11-01)

Histone Lysine Methylation and Long Non-Coding RNA: The New Target Players in Skeletal Muscle Cell Regeneration
by: Magdaleena Naemi Mbadhi, et al.
Published: (2021-12-01)

Features of molecular mechanisms of insulin resistance pathogenesis in various tissues in obesity
by: D. I. Kuzmenko, et al.
Published: (2023-04-01)

Deletion of miPEP in adipocytes protects against obesity and insulin resistance by boosting muscle metabolism
by: Alexis Diaz-Vegas, et al.
Published: (2024-08-01)

Gut Microbiota Composition Is Associated With the Global DNA Methylation Pattern in Obesity
by: Bruno Ramos-Molina, et al.
Published: (2019-07-01)

Aberrant DNA methylation involved in obese women with systemic insulin resistance
by: Zhang Shao-Jun, et al.
Published: (2018-06-01)

Skeletal Muscle Uncoupling Proteins in Mice Models of Obesity
by: Lidija Križančić Bombek, et al.
Published: (2022-03-01)

Mitochondrial Abundance and Function Differ Across Muscle Within Species
by: Con-Ning Yen, et al.
Published: (2024-10-01)

Genome-wide characterization of mitochondrial DNA methylation in human brain
by: Matthew Devall, et al.
Published: (2023-01-01)

Mitochondrial Genetics and Epigenetics in Osteoarthritis
by: Ignacio Rego-Pérez, et al.
Published: (2020-01-01)

Pharmacological inhibition of dynamin‐related protein 1 attenuates skeletal muscle insulin resistance in obesity
by: Benjamin A. Kugler, et al.
Published: (2021-04-01)

The Change of Skeletal Muscle Caused by Inflammation in Obesity as the Key Path to Fibrosis: Thoughts on Mechanisms and Intervention Strategies
by: Yixuan Li, et al.
Published: (2024-12-01)

Influence of Obesity and Type 2 Diabetes on Calcium Handling by Skeletal Muscle: Spotlight on the Sarcoplasmic Reticulum and Mitochondria
by: Hiroaki Eshima
Published: (2021-11-01)