Haemodynamics-driven developmental pruning of brain vasculature in zebrafish.

The brain blood vasculature consists of a highly ramified vessel network that is tailored to meet its physiological functions. How the brain vasculature is formed has long been fascinating biologists. Here we report that the developing vasculature in the zebrafish midbrain undergoes not only angioge...

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Bibliographic Details
Main Authors: Qi Chen, Luan Jiang, Chun Li, Dan Hu, Ji-wen Bu, David Cai, Jiu-lin Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3419171?pdf=render