Designing a microbial fermentation-functionalized alginate microsphere for targeted release of 5-ASA using nano dietary fiber carrier for inflammatory bowel disease treatment

Designing a microbial fermentation-functionalized alginate microsphere for targeted release of 5-ASA using nano dietary fiber carrier for inflammatory bowel disease treatment

Abstract Patients with inflammatory bowel disease (IBD) always suffer from severe abdominal pain and appear to be at high risk for colorectal cancer. Recently, the co-delivery of targeted drugs and gut microbiota has developed into an attractive strategy. A new strategy using gut microbiota fermenta...

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Bibliographic Details
Main Authors: Lei Qiu, Renbin Shen, Lei Wei, Shujuan Xu, Wei Xia, Yan Hou, Jinxin Cui, Rong Qu, Jiale Luo, Jian Cao, Jie Yang, Jing Sun, Ronglin Ma, Qiang Yu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Nanobiotechnology
Subjects:
Nano dietary fibers
Colitis targeting
Gut microbiota
5-ASA
Gel microspheres
Online Access:https://doi.org/10.1186/s12951-023-02097-6

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