Fixed drug eruption due to clarithromycin
Fixed drug eruption (FDE) is an unusual adverse effect of any drug, especially antibiotics like clarithromycin. Herein we report a case of clarithromycin induced FDE in a 30-year-old man who presented with recurrent erythematous and pruritic cutaneous lesions on the lower lip, right hand and left th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Journal of Research in Pharmacy Practice |
| Subjects: | |
| Online Access: | http://www.jrpp.net/article.asp?issn=2319-9644;year=2013;volume=2;issue=4;spage=169;epage=171;aulast=Malkarnekar |
| _version_ | 1819115058047746048 |
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| author | Santoshi Balkrishna Malkarnekar L Naveen |
| author_facet | Santoshi Balkrishna Malkarnekar L Naveen |
| author_sort | Santoshi Balkrishna Malkarnekar |
| collection | DOAJ |
| description | Fixed drug eruption (FDE) is an unusual adverse effect of any drug, especially antibiotics like clarithromycin. Herein we report a case of clarithromycin induced FDE in a 30-year-old man who presented with recurrent erythematous and pruritic cutaneous lesions on the lower lip, right hand and left thigh. The lesions were initially misdiagnosed as lichen planus and treated with topical steroids. Each recurrence was at the same site and the lesions faded within 2 weeks leaving behind violacceous pigmentation. All the cutaneous lesions were reproduced following an oral provocation test thus confirming the diagnosis of clarithromycin induced FDE, which is a rare occurrence. When it does occur, it is often misdiagnosed, so physicians should be aware of this condition in order to prevent future recurrences as it causes a lot of cosmetic and physical discomfort to the patient. |
| first_indexed | 2024-12-22T04:55:09Z |
| format | Article |
| id | doaj.art-852ba66d65bb4f8e8e5a373608ee6ab9 |
| institution | Directory Open Access Journal |
| issn | 2319-9644 2279-042X |
| language | English |
| last_indexed | 2024-12-22T04:55:09Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Research in Pharmacy Practice |
| spelling | doaj.art-852ba66d65bb4f8e8e5a373608ee6ab92022-12-21T18:38:24ZengWolters Kluwer Medknow PublicationsJournal of Research in Pharmacy Practice2319-96442279-042X2013-01-012416917110.4103/2279-042X.128152Fixed drug eruption due to clarithromycinSantoshi Balkrishna MalkarnekarL NaveenFixed drug eruption (FDE) is an unusual adverse effect of any drug, especially antibiotics like clarithromycin. Herein we report a case of clarithromycin induced FDE in a 30-year-old man who presented with recurrent erythematous and pruritic cutaneous lesions on the lower lip, right hand and left thigh. The lesions were initially misdiagnosed as lichen planus and treated with topical steroids. Each recurrence was at the same site and the lesions faded within 2 weeks leaving behind violacceous pigmentation. All the cutaneous lesions were reproduced following an oral provocation test thus confirming the diagnosis of clarithromycin induced FDE, which is a rare occurrence. When it does occur, it is often misdiagnosed, so physicians should be aware of this condition in order to prevent future recurrences as it causes a lot of cosmetic and physical discomfort to the patient.http://www.jrpp.net/article.asp?issn=2319-9644;year=2013;volume=2;issue=4;spage=169;epage=171;aulast=MalkarnekarClarithromycin; fixed drug eruption; oral provocation test |
| spellingShingle | Santoshi Balkrishna Malkarnekar L Naveen Fixed drug eruption due to clarithromycin Journal of Research in Pharmacy Practice Clarithromycin; fixed drug eruption; oral provocation test |
| title | Fixed drug eruption due to clarithromycin |
| title_full | Fixed drug eruption due to clarithromycin |
| title_fullStr | Fixed drug eruption due to clarithromycin |
| title_full_unstemmed | Fixed drug eruption due to clarithromycin |
| title_short | Fixed drug eruption due to clarithromycin |
| title_sort | fixed drug eruption due to clarithromycin |
| topic | Clarithromycin; fixed drug eruption; oral provocation test |
| url | http://www.jrpp.net/article.asp?issn=2319-9644;year=2013;volume=2;issue=4;spage=169;epage=171;aulast=Malkarnekar |
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