Small Molecule GSK-3 Inhibitors Safely Promote the Proliferation and Viability of Human Dental Pulp Stem Cells—In Vitro

Small Molecule GSK-3 Inhibitors Safely Promote the Proliferation and Viability of Human Dental Pulp Stem Cells—In Vitro

Small molecules have demonstrated promising results as successful alternatives to growth factors. In this study, focus was drawn to CHIR99021 and tideglusib as GSK-3 inhibitors known for their anti-inflammatory and regenerative potential. The effect of both tideglusib and CHIR99021 on the proliferat...

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Bibliographic Details
Main Authors: Samer Hanna, Riham Aly, Ghada Nour Eldeen, Alberto Adanero Velasco, Ruth Pérez Alfayate
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
CHIR99021
drug repurposing
GSK3 inhibitors
hDPSCs
tideglusib
<i>Wnt</i> pathway
Online Access:https://www.mdpi.com/2227-9059/11/2/542

Internet

https://www.mdpi.com/2227-9059/11/2/542

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