Unusual Rapid Growth of Primary Splenic Diffuse Large B-Cell Lymphoma with Extensive Necrosis
The primary splenic lymphoma is extremely uncommon with an incidence rate of <1% of all the lymphomas under the strict criteria for diagnosis expounded by Das Gupta et al. Clinical presentations of nonspecific symptoms are weight loss, weakness, fever, and left upper quadrant pain or discomfort d...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/1/35 |
| _version_ | 1797626045887676416 |
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| author | Yue-Ren Chen Hwa-Koon Wu Yang-Yuan Chen |
| author_facet | Yue-Ren Chen Hwa-Koon Wu Yang-Yuan Chen |
| author_sort | Yue-Ren Chen |
| collection | DOAJ |
| description | The primary splenic lymphoma is extremely uncommon with an incidence rate of <1% of all the lymphomas under the strict criteria for diagnosis expounded by Das Gupta et al. Clinical presentations of nonspecific symptoms are weight loss, weakness, fever, and left upper quadrant pain or discomfort due to enlarged spleen. Abdominal ultrasound and CT are the most widely used imaging modality for the assessment of lymphoma. The imaged features of splenic lymphoma are nonspecific; typical lymphoma presents as a diffusely enlarged spleen. The abdominal CT scan in our case showed a large cystic splenic mass measuring 14 cm without enhancement after contrast medium. Lymphoma is often described as an aggressive tumor because its rapid doubling time can quickly increase the size of a tumor. In our case, the tumor grew to more than 100 times its original size in 4 months. So, we present this unusual rapid growth of primary splenic lymphoma. |
| first_indexed | 2024-03-11T10:05:03Z |
| format | Article |
| id | doaj.art-852df55afcae4d22957ee38998f0cb3a |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T10:05:03Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-852df55afcae4d22957ee38998f0cb3a2023-11-16T15:07:56ZengMDPI AGDiagnostics2075-44182022-12-011313510.3390/diagnostics13010035Unusual Rapid Growth of Primary Splenic Diffuse Large B-Cell Lymphoma with Extensive NecrosisYue-Ren Chen0Hwa-Koon Wu1Yang-Yuan Chen2Division of Internal Medicine, Yuan-Lin Christian Hospital, 456 Ju-Guang Road, Yuan-Lin City 510012, TaiwanDivision of Radiology, Changhua Christian Hospital, 135 Nan-Xiao Street, Changhua City 50006, TaiwanDivision of Gastroenterology, Changhua and Yuan-Lin Christian Hospital, 135 Nanxiao Street, Changhua City 50006, TaiwanThe primary splenic lymphoma is extremely uncommon with an incidence rate of <1% of all the lymphomas under the strict criteria for diagnosis expounded by Das Gupta et al. Clinical presentations of nonspecific symptoms are weight loss, weakness, fever, and left upper quadrant pain or discomfort due to enlarged spleen. Abdominal ultrasound and CT are the most widely used imaging modality for the assessment of lymphoma. The imaged features of splenic lymphoma are nonspecific; typical lymphoma presents as a diffusely enlarged spleen. The abdominal CT scan in our case showed a large cystic splenic mass measuring 14 cm without enhancement after contrast medium. Lymphoma is often described as an aggressive tumor because its rapid doubling time can quickly increase the size of a tumor. In our case, the tumor grew to more than 100 times its original size in 4 months. So, we present this unusual rapid growth of primary splenic lymphoma.https://www.mdpi.com/2075-4418/13/1/35primary splenic lymphomacystic splenic massdoubling time |
| spellingShingle | Yue-Ren Chen Hwa-Koon Wu Yang-Yuan Chen Unusual Rapid Growth of Primary Splenic Diffuse Large B-Cell Lymphoma with Extensive Necrosis Diagnostics primary splenic lymphoma cystic splenic mass doubling time |
| title | Unusual Rapid Growth of Primary Splenic Diffuse Large B-Cell Lymphoma with Extensive Necrosis |
| title_full | Unusual Rapid Growth of Primary Splenic Diffuse Large B-Cell Lymphoma with Extensive Necrosis |
| title_fullStr | Unusual Rapid Growth of Primary Splenic Diffuse Large B-Cell Lymphoma with Extensive Necrosis |
| title_full_unstemmed | Unusual Rapid Growth of Primary Splenic Diffuse Large B-Cell Lymphoma with Extensive Necrosis |
| title_short | Unusual Rapid Growth of Primary Splenic Diffuse Large B-Cell Lymphoma with Extensive Necrosis |
| title_sort | unusual rapid growth of primary splenic diffuse large b cell lymphoma with extensive necrosis |
| topic | primary splenic lymphoma cystic splenic mass doubling time |
| url | https://www.mdpi.com/2075-4418/13/1/35 |
| work_keys_str_mv | AT yuerenchen unusualrapidgrowthofprimarysplenicdiffuselargebcelllymphomawithextensivenecrosis AT hwakoonwu unusualrapidgrowthofprimarysplenicdiffuselargebcelllymphomawithextensivenecrosis AT yangyuanchen unusualrapidgrowthofprimarysplenicdiffuselargebcelllymphomawithextensivenecrosis |