Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare System
Exploring differences in clinical outcomes based on race and origin among patients hospitalized for COVID-19 is a controversial issue. The ALC COVID-19 Registry includes all confirmed COVID-19 patients admitted to hospital from 3 March 2020 to 17 December 2020. The data were obtained from electronic...
| Asıl Yazarlar: | , , , , , , , , , , , , , |
|---|---|
| Materyal Türü: | Makale |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
MDPI AG
2021-08-01
|
| Seri Bilgileri: | Microorganisms |
| Konular: | |
| Online Erişim: | https://www.mdpi.com/2076-2607/9/8/1772 |
| _version_ | 1827684659566215168 |
|---|---|
| author | Silvia Otero-Rodriguez Oscar Moreno-Pérez Jose Manuel Ramos Mar García Vicente Boix Sergio Reus Diego Torrus Pablo Chico-Sánchez José Sánchez-Payá Fernando Aldana-Macias Joan Gil Joaquín Portilla Esperanza Merino on behalf of COVID19 ALC Research Group |
| author_facet | Silvia Otero-Rodriguez Oscar Moreno-Pérez Jose Manuel Ramos Mar García Vicente Boix Sergio Reus Diego Torrus Pablo Chico-Sánchez José Sánchez-Payá Fernando Aldana-Macias Joan Gil Joaquín Portilla Esperanza Merino on behalf of COVID19 ALC Research Group |
| author_sort | Silvia Otero-Rodriguez |
| collection | DOAJ |
| description | Exploring differences in clinical outcomes based on race and origin among patients hospitalized for COVID-19 is a controversial issue. The ALC COVID-19 Registry includes all confirmed COVID-19 patients admitted to hospital from 3 March 2020 to 17 December 2020. The data were obtained from electronic health records in order to evaluate the differences in the clinical features and outcomes among European and Latin American patients. The follow-ups occurred after 156 days. A propensity score weighting (PSW) logistic regression model was used to estimate the odds ratio (OR, 95% CI) for Latin American origin and outcome associations. Of the 696 patients included, 46.7% were women, with a median age of 65 (IQR 53–67) years, 614 (88.2%) were European, and 82 (11.8%) were Latin American. Latin American patients were younger, with fewer comorbidities, and a higher incidence of extensive pneumonia. After adjusting for residual confounders, Latin American origin was not associated with an increased risk of death (PSW OR 0.85 (0.23–3.14)) or with the need for invasive mechanical ventilation (PSW OR 0.35 (0.12–1.03)). Latin American origin was associated with a shorter hospital stay, but without differences in how long the patient remained on mechanical ventilation. In a public healthcare system, the rates of death or mechanical ventilation in severe COVID-19 cases were found to be comparable between patients of European and Latin American origins. |
| first_indexed | 2024-03-10T08:34:18Z |
| format | Article |
| id | doaj.art-8532b4a364f64d40abb94dba99d3bc6e |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T08:34:18Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-8532b4a364f64d40abb94dba99d3bc6e2023-11-22T08:48:39ZengMDPI AGMicroorganisms2076-26072021-08-0198177210.3390/microorganisms9081772Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare SystemSilvia Otero-Rodriguez0Oscar Moreno-Pérez1Jose Manuel Ramos2Mar García3Vicente Boix4Sergio Reus5Diego Torrus6Pablo Chico-Sánchez7José Sánchez-Payá8Fernando Aldana-Macias9Joan Gil10Joaquín Portilla11Esperanza Merino12on behalf of COVID19 ALC Research GroupAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainAlicante Institute of Health and Biomedical Research (ISABIAL), 03010 Alicante, SpainExploring differences in clinical outcomes based on race and origin among patients hospitalized for COVID-19 is a controversial issue. The ALC COVID-19 Registry includes all confirmed COVID-19 patients admitted to hospital from 3 March 2020 to 17 December 2020. The data were obtained from electronic health records in order to evaluate the differences in the clinical features and outcomes among European and Latin American patients. The follow-ups occurred after 156 days. A propensity score weighting (PSW) logistic regression model was used to estimate the odds ratio (OR, 95% CI) for Latin American origin and outcome associations. Of the 696 patients included, 46.7% were women, with a median age of 65 (IQR 53–67) years, 614 (88.2%) were European, and 82 (11.8%) were Latin American. Latin American patients were younger, with fewer comorbidities, and a higher incidence of extensive pneumonia. After adjusting for residual confounders, Latin American origin was not associated with an increased risk of death (PSW OR 0.85 (0.23–3.14)) or with the need for invasive mechanical ventilation (PSW OR 0.35 (0.12–1.03)). Latin American origin was associated with a shorter hospital stay, but without differences in how long the patient remained on mechanical ventilation. In a public healthcare system, the rates of death or mechanical ventilation in severe COVID-19 cases were found to be comparable between patients of European and Latin American origins.https://www.mdpi.com/2076-2607/9/8/1772COVID-19originraceLatin Americanmortalityoutcome |
| spellingShingle | Silvia Otero-Rodriguez Oscar Moreno-Pérez Jose Manuel Ramos Mar García Vicente Boix Sergio Reus Diego Torrus Pablo Chico-Sánchez José Sánchez-Payá Fernando Aldana-Macias Joan Gil Joaquín Portilla Esperanza Merino on behalf of COVID19 ALC Research Group Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare System Microorganisms COVID-19 origin race Latin American mortality outcome |
| title | Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare System |
| title_full | Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare System |
| title_fullStr | Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare System |
| title_full_unstemmed | Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare System |
| title_short | Latin American Origin Is Not Associated with Worse Outcomes among Hospitalized Patients with COVID-19 in a Public Healthcare System |
| title_sort | latin american origin is not associated with worse outcomes among hospitalized patients with covid 19 in a public healthcare system |
| topic | COVID-19 origin race Latin American mortality outcome |
| url | https://www.mdpi.com/2076-2607/9/8/1772 |
| work_keys_str_mv | AT silviaoterorodriguez latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT oscarmorenoperez latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT josemanuelramos latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT margarcia latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT vicenteboix latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT sergioreus latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT diegotorrus latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT pablochicosanchez latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT josesanchezpaya latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT fernandoaldanamacias latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT joangil latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT joaquinportilla latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT esperanzamerino latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem AT onbehalfofcovid19alcresearchgroup latinamericanoriginisnotassociatedwithworseoutcomesamonghospitalizedpatientswithcovid19inapublichealthcaresystem |