Molecularly Imprinted Polymer-Coated Inorganic Nanoparticles: Fabrication and Biomedical Applications
Molecularly imprinted polymers (MIPs) continue to gain increasing attention as functional materials due to their unique characteristics such as higher stability, simple preparation, robustness, better binding capacity, and low cost. In particular, MIP-coated inorganic nanoparticles have emerged as a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Micromachines |
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| Online Access: | https://www.mdpi.com/2072-666X/13/9/1464 |
| _version_ | 1797484685927907328 |
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| author | Sinem Orbay Ozgur Kocaturk Rana Sanyal Amitav Sanyal |
| author_facet | Sinem Orbay Ozgur Kocaturk Rana Sanyal Amitav Sanyal |
| author_sort | Sinem Orbay |
| collection | DOAJ |
| description | Molecularly imprinted polymers (MIPs) continue to gain increasing attention as functional materials due to their unique characteristics such as higher stability, simple preparation, robustness, better binding capacity, and low cost. In particular, MIP-coated inorganic nanoparticles have emerged as a promising platform for various biomedical applications ranging from drug delivery to bioimaging. The integration of MIPs with inorganic nanomaterials such as silica (SiO<sub>2</sub>), iron oxide (Fe<sub>3</sub>O<sub>4</sub>), gold (Au), silver (Ag), and quantum dots (QDs) combines several attributes from both components to yield highly multifunctional materials. These materials with a multicomponent hierarchical structure composed of an inorganic core and an imprinted polymer shell exhibit enhanced properties and new functionalities. This review aims to provide a general overview of key recent advances in the fabrication of MIPs-coated inorganic nanoparticles and highlight their biomedical applications, including drug delivery, biosensor, bioimaging, and bioseparation. |
| first_indexed | 2024-03-09T23:07:57Z |
| format | Article |
| id | doaj.art-85335a119a144c9c82e22b8c1422a4c2 |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-03-09T23:07:57Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-85335a119a144c9c82e22b8c1422a4c22023-11-23T17:49:57ZengMDPI AGMicromachines2072-666X2022-09-01139146410.3390/mi13091464Molecularly Imprinted Polymer-Coated Inorganic Nanoparticles: Fabrication and Biomedical ApplicationsSinem Orbay0Ozgur Kocaturk1Rana Sanyal2Amitav Sanyal3Institute of Biomedical Engineering, Bogazici University, Istanbul 34684, TurkeyInstitute of Biomedical Engineering, Bogazici University, Istanbul 34684, TurkeyDepartment of Chemistry, Center for Life Sciences and Technologies, Bogazici University, Istanbul 34342, TurkeyDepartment of Chemistry, Center for Life Sciences and Technologies, Bogazici University, Istanbul 34342, TurkeyMolecularly imprinted polymers (MIPs) continue to gain increasing attention as functional materials due to their unique characteristics such as higher stability, simple preparation, robustness, better binding capacity, and low cost. In particular, MIP-coated inorganic nanoparticles have emerged as a promising platform for various biomedical applications ranging from drug delivery to bioimaging. The integration of MIPs with inorganic nanomaterials such as silica (SiO<sub>2</sub>), iron oxide (Fe<sub>3</sub>O<sub>4</sub>), gold (Au), silver (Ag), and quantum dots (QDs) combines several attributes from both components to yield highly multifunctional materials. These materials with a multicomponent hierarchical structure composed of an inorganic core and an imprinted polymer shell exhibit enhanced properties and new functionalities. This review aims to provide a general overview of key recent advances in the fabrication of MIPs-coated inorganic nanoparticles and highlight their biomedical applications, including drug delivery, biosensor, bioimaging, and bioseparation.https://www.mdpi.com/2072-666X/13/9/1464molecularly imprinted polymersinorganic nanoparticlesbiomedical applications |
| spellingShingle | Sinem Orbay Ozgur Kocaturk Rana Sanyal Amitav Sanyal Molecularly Imprinted Polymer-Coated Inorganic Nanoparticles: Fabrication and Biomedical Applications Micromachines molecularly imprinted polymers inorganic nanoparticles biomedical applications |
| title | Molecularly Imprinted Polymer-Coated Inorganic Nanoparticles: Fabrication and Biomedical Applications |
| title_full | Molecularly Imprinted Polymer-Coated Inorganic Nanoparticles: Fabrication and Biomedical Applications |
| title_fullStr | Molecularly Imprinted Polymer-Coated Inorganic Nanoparticles: Fabrication and Biomedical Applications |
| title_full_unstemmed | Molecularly Imprinted Polymer-Coated Inorganic Nanoparticles: Fabrication and Biomedical Applications |
| title_short | Molecularly Imprinted Polymer-Coated Inorganic Nanoparticles: Fabrication and Biomedical Applications |
| title_sort | molecularly imprinted polymer coated inorganic nanoparticles fabrication and biomedical applications |
| topic | molecularly imprinted polymers inorganic nanoparticles biomedical applications |
| url | https://www.mdpi.com/2072-666X/13/9/1464 |
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