A critical role of AREG for bleomycin-induced skin fibrosis

A critical role of AREG for bleomycin-induced skin fibrosis

Abstract We report our discovery of an important player in the development of skin fibrosis, a hallmark of scleroderma. Scleroderma is a fibrotic disease, affecting 70,000 to 150,000 Americans. Fibrosis is a pathological wound healing process that produces an excessive extracellular matrix to interf...

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Bibliographic Details
Main Authors: Mary Yinghua Zhang, Shuyi Fang, Hongyu Gao, Xiaoli Zhang, Dongsheng Gu, Yunlong Liu, Jun Wan, Jingwu Xie
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Cell & Bioscience
Subjects:
Scleroderma
Skin fibrosis
Bleomycin
Areg
MEK
Online Access:https://doi.org/10.1186/s13578-021-00553-0

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