Tanshinone IIA inhibits proliferation and migration by downregulation of the PI3K/Akt pathway in small cell lung cancer cells

Tanshinone IIA inhibits proliferation and migration by downregulation of the PI3K/Akt pathway in small cell lung cancer cells

Abstract Background Small cell lung cancer (SCLC) is the most malignant lung cancer type. Due to the high rates of metastasis and drug resistance, effective therapeutic strategies remain lacking. Tanshinone IIA (Tan IIA) has been reported to exhibit anti-tumor activity. Therefore, this study investi...

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Bibliographic Details
Main Authors: Yuxin Jiang, Yanli Bi, Lingjie Zhou, Senwen Zheng, Tingting Jian, Jian Chen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Tanshinone IIA
Small cell lung cancer
Metastasis
Epithelial-to-mesenchymal transition
PI3K
Akt
Online Access:https://doi.org/10.1186/s12906-024-04363-y

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