Super-enhancer-driven lncRNA-DAW promotes liver cancer cell proliferation through activation of Wnt/β-catenin pathway

Super-enhancer-driven lncRNA-DAW promotes liver cancer cell proliferation through activation of Wnt/β-catenin pathway

Aberrant expression of long non-coding RNAs (lncRNAs) has been reported in multiple cancers. However, the underlying mechanisms mediated by super-enhancers remain elusive. Here we sought to define the role of a novel lncRNA termed lncRNA-DAW in tumorigenesis. Our results revealed that lncRNA-DAW was...

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Bibliographic Details
Main Authors: Weicheng Liang, Chuanjian Shi, Weilong Hong, Panlong Li, Xue Zhou, Weiming Fu, Lizhu Lin, Jinfang Zhang
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
cell growth
lncRNA
super-enhancer
Wnt/β-catenin pathway
liver cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121002717

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