Importance of Biochemical Markers in Postmenopausal and Senile Osteoporosis
Recently, the biochemical markers are widely used in order to evaluate the bone turnover. This study was planned to investigate the role of biochemical markers and Bone Mineral Density(BMD) in postmenopausal (PMO) and senile osteoporosis (SO) patients. A total of 86 patients( 44 PMO, 42 SO), ages r...
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2002-12-01
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| Series: | Türk Osteoporoz Dergisi |
| Subjects: | |
| Online Access: | http://www.turkosteoporozdergisi.org/article_4075/Importance-Of-Biochemical-Markers-In-Postmenopausal-And-Senile-Osteoporosis |
| _version_ | 1797916162451832832 |
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| author | Deniz Evcik Mustafa Serteser |
| author_facet | Deniz Evcik Mustafa Serteser |
| author_sort | Deniz Evcik |
| collection | DOAJ |
| description | Recently, the biochemical markers are widely used in order to evaluate the bone turnover. This study was planned to investigate the role of biochemical markers and Bone Mineral Density(BMD) in postmenopausal (PMO) and senile osteoporosis (SO) patients. A total of 86 patients( 44 PMO, 42 SO), ages ranged between 39-79 were included in this study. Alkaline phosphatase (ALP) and osteocalcin levels were determined from blood samples. Urinary deoxypyridinoline(Dpd) and creatinine(cr) concentration were examined and the ratio of Dpd/cr was calculated. Also BMD of the patients were measured from L1-L4 and proximal femur and t score were determined. There was no statistical difference in ALP levels between two groups. Osteocalcine and Dpd/cr levels were statistically increased in PMO group(p<0.001). According to BMD t score which was measured from proximal femur was significantly higher in SO patients(p<0.05). Our results show that biochemical markers are useful for the assessment of high-turnover osteoporosis. |
| first_indexed | 2024-04-10T12:52:56Z |
| format | Article |
| id | doaj.art-853cd56ffb0d43fc8df7988b8e7261ea |
| institution | Directory Open Access Journal |
| issn | 2147-2653 |
| language | English |
| last_indexed | 2024-04-10T12:52:56Z |
| publishDate | 2002-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Osteoporoz Dergisi |
| spelling | doaj.art-853cd56ffb0d43fc8df7988b8e7261ea2023-02-15T16:13:38ZengGalenos YayineviTürk Osteoporoz Dergisi2147-26532002-12-0184182185Importance of Biochemical Markers in Postmenopausal and Senile OsteoporosisDeniz Evcik0Mustafa Serteser1Afyon Kocatepe Üniversitesi Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim DalıAfyon Kocatepe Üniversitesi Tıp Fakültesi, Biyokimya Anabilim DalıRecently, the biochemical markers are widely used in order to evaluate the bone turnover. This study was planned to investigate the role of biochemical markers and Bone Mineral Density(BMD) in postmenopausal (PMO) and senile osteoporosis (SO) patients. A total of 86 patients( 44 PMO, 42 SO), ages ranged between 39-79 were included in this study. Alkaline phosphatase (ALP) and osteocalcin levels were determined from blood samples. Urinary deoxypyridinoline(Dpd) and creatinine(cr) concentration were examined and the ratio of Dpd/cr was calculated. Also BMD of the patients were measured from L1-L4 and proximal femur and t score were determined. There was no statistical difference in ALP levels between two groups. Osteocalcine and Dpd/cr levels were statistically increased in PMO group(p<0.001). According to BMD t score which was measured from proximal femur was significantly higher in SO patients(p<0.05). Our results show that biochemical markers are useful for the assessment of high-turnover osteoporosis.http://www.turkosteoporozdergisi.org/article_4075/Importance-Of-Biochemical-Markers-In-Postmenopausal-And-Senile-OsteoporosisPostmenopausal-senile osteoporosisbiochemical markersbone mineral density |
| spellingShingle | Deniz Evcik Mustafa Serteser Importance of Biochemical Markers in Postmenopausal and Senile Osteoporosis Türk Osteoporoz Dergisi Postmenopausal-senile osteoporosis biochemical markers bone mineral density |
| title | Importance of Biochemical Markers in Postmenopausal and Senile Osteoporosis |
| title_full | Importance of Biochemical Markers in Postmenopausal and Senile Osteoporosis |
| title_fullStr | Importance of Biochemical Markers in Postmenopausal and Senile Osteoporosis |
| title_full_unstemmed | Importance of Biochemical Markers in Postmenopausal and Senile Osteoporosis |
| title_short | Importance of Biochemical Markers in Postmenopausal and Senile Osteoporosis |
| title_sort | importance of biochemical markers in postmenopausal and senile osteoporosis |
| topic | Postmenopausal-senile osteoporosis biochemical markers bone mineral density |
| url | http://www.turkosteoporozdergisi.org/article_4075/Importance-Of-Biochemical-Markers-In-Postmenopausal-And-Senile-Osteoporosis |
| work_keys_str_mv | AT denizevcik importanceofbiochemicalmarkersinpostmenopausalandsenileosteoporosis AT mustafaserteser importanceofbiochemicalmarkersinpostmenopausalandsenileosteoporosis |