NLR-Dependent Regulation of Inflammation in Multiple Sclerosis

NLR-Dependent Regulation of Inflammation in Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) associated with inappropriate activation of lymphocytes, hyperinflammatory responses, demyelination, and neuronal damage. In the past decade, a number of biological immunomodulators have been developed that suppress...

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Bibliographic Details
Main Authors: Marjan Gharagozloo, Katsiaryna V. Gris, Tara Mahvelati, Abdelaziz Amrani, John R. Lukens, Denis Gris
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
NLRs
multiple sclerosis
NLRP3
NLRP12
NLRX1
inflammation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.02012/full

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