Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus

Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus

Numerous large DNA viruses have evolved sophisticated countermeasures to hijack the premature programmed cell death of host cells post-infection, including the expression of proteins homologous in sequence, structure, or function to cellular Bcl-2 proteins. Kaposi sarcoma herpes virus (KSHV), a memb...

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Bibliographic Details
Main Authors: Chathura D. Suraweera, Mark G. Hinds, Marc Kvansakul
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Viruses
Subjects:
Bcl-2
apoptosis
Bid
Kaposi Sarcoma Herpesvirus
herpesviruses
X-ray crystallography
Online Access:https://www.mdpi.com/1999-4915/14/4/738

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