A case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significance
Monoclonal gammopathy of renal significance is a relatively new diagnosis that attributes kidney disease to damage caused by a monoclonal protein. There is growing recognition of this disease in patients previously diagnosed with monoclonal gammopathy of undetermined significance, as they increasing...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Greater Baltimore Medical Center
2021-01-01
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| Series: | Journal of Community Hospital Internal Medicine Perspectives |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/20009666.2020.1831744 |
| _version_ | 1828082163171459072 |
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| author | Victoria Campdesuner Yeshanew Teklie Natalia Lattanzio Christian Lorenzo Stephen Bell Yorlenis Rodriguez Ashok Sastry |
| author_facet | Victoria Campdesuner Yeshanew Teklie Natalia Lattanzio Christian Lorenzo Stephen Bell Yorlenis Rodriguez Ashok Sastry |
| author_sort | Victoria Campdesuner |
| collection | DOAJ |
| description | Monoclonal gammopathy of renal significance is a relatively new diagnosis that attributes kidney disease to damage caused by a monoclonal protein. There is growing recognition of this disease in patients previously diagnosed with monoclonal gammopathy of undetermined significance, as they increasingly develop clinically significant renal impairment requiring treatment. We outline a case of a patient presenting with worsening renal function, found to have a circulating monoclonal protein and ultimately diagnosed with a subtype of monoclonal gammopathy of renal significance referred to as immunotactoid glomerulopathy. Abbreviations: MGUS: Monoclonal gammopathy of undetermined significance; M-protein: Monoclonal protein; MM: Multiple myeloma; MGRS: Monoclonal gammopathy of renal significance; MGCS: Monoclonal gammopathy of clinical significance; CKD: Chronic kidney disease; C3 and C4: Complement 3 and complement 4, respectively; EF: Ejection fraction; CT: Computed tomography; IgG: Immunoglobulin G; GFR: Glomerular filtration rate; PET: Positron emission tomography; MRI: Magnetic Resonance Imaging. |
| first_indexed | 2024-04-11T03:46:34Z |
| format | Article |
| id | doaj.art-8545ddfa025b4a04816aa552f8ad8ecd |
| institution | Directory Open Access Journal |
| issn | 2000-9666 |
| language | English |
| last_indexed | 2024-04-11T03:46:34Z |
| publishDate | 2021-01-01 |
| publisher | Greater Baltimore Medical Center |
| record_format | Article |
| series | Journal of Community Hospital Internal Medicine Perspectives |
| spelling | doaj.art-8545ddfa025b4a04816aa552f8ad8ecd2023-01-02T02:39:46ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662021-01-01111606410.1080/20009666.2020.18317441831744A case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significanceVictoria Campdesuner0Yeshanew Teklie1Natalia Lattanzio2Christian Lorenzo3Stephen Bell4Yorlenis Rodriguez5Ashok Sastry6Sarasota Memorial HospitalSarasota Memorial HospitalSarasota Memorial HospitalSarasota Memorial HospitalSarasota Memorial HospitalSarasota Memorial HospitalSarasota Memorial HospitalMonoclonal gammopathy of renal significance is a relatively new diagnosis that attributes kidney disease to damage caused by a monoclonal protein. There is growing recognition of this disease in patients previously diagnosed with monoclonal gammopathy of undetermined significance, as they increasingly develop clinically significant renal impairment requiring treatment. We outline a case of a patient presenting with worsening renal function, found to have a circulating monoclonal protein and ultimately diagnosed with a subtype of monoclonal gammopathy of renal significance referred to as immunotactoid glomerulopathy. Abbreviations: MGUS: Monoclonal gammopathy of undetermined significance; M-protein: Monoclonal protein; MM: Multiple myeloma; MGRS: Monoclonal gammopathy of renal significance; MGCS: Monoclonal gammopathy of clinical significance; CKD: Chronic kidney disease; C3 and C4: Complement 3 and complement 4, respectively; EF: Ejection fraction; CT: Computed tomography; IgG: Immunoglobulin G; GFR: Glomerular filtration rate; PET: Positron emission tomography; MRI: Magnetic Resonance Imaging.http://dx.doi.org/10.1080/20009666.2020.1831744monoclonal gammopathy of renal significanceimmunotactoid glomerulopathy |
| spellingShingle | Victoria Campdesuner Yeshanew Teklie Natalia Lattanzio Christian Lorenzo Stephen Bell Yorlenis Rodriguez Ashok Sastry A case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significance Journal of Community Hospital Internal Medicine Perspectives monoclonal gammopathy of renal significance immunotactoid glomerulopathy |
| title | A case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significance |
| title_full | A case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significance |
| title_fullStr | A case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significance |
| title_full_unstemmed | A case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significance |
| title_short | A case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significance |
| title_sort | case of immunotactoid glomerulopathy in a patient with monoclonal gammopathy of renal significance |
| topic | monoclonal gammopathy of renal significance immunotactoid glomerulopathy |
| url | http://dx.doi.org/10.1080/20009666.2020.1831744 |
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