Comparison of suspected Lynch syndrome patients carrying BRCA and BRCA‐like variants with Lynch syndrome probands: Phenotypic characteristics and pedigree analyses

Comparison of suspected Lynch syndrome patients carrying BRCA and BRCA‐like variants with Lynch syndrome probands: Phenotypic characteristics and pedigree analyses

Abstract Background Colorectal cancer (CRC) patients diagnosed with Lynch syndrome (LS) are recommended genetic testing. Increasing numbers of germline variants involved in homologous recombination have been identified in suspected LS patients. This study compared phenotypic the characteristics of s...

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Bibliographic Details
Main Authors: Yun Xu, Cong Li, Zhimin Wang, Fangqi Liu, Ye Xu
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
BRCA
BRCA‐like
colorectal cancer
Lynch syndrome
mismatch repair
Online Access:https://doi.org/10.1002/mgg3.1359

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