Ubiquitination of Major Histocompatibility Complex II Changes Its Immunological Recognition Structure

Ubiquitination of Major Histocompatibility Complex II Changes Its Immunological Recognition Structure

Ubiquitination is a process that dictates the lifespan of major histocompatibility complex class II (MHC II)/peptide complexes on antigen-presenting cells. This process is tightly controlled by the levels of ubiquitin ligases, and disruptions in the turnover of MHC II can lead to the improper develo...

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Bibliographic Details
Main Authors: Yuko Kozono, Masahiro Kuramochi, Yuji C. Sasaki, Haruo Kozono
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
ubiquitin ligase
MHC
dendritic cells
LAG-3
single-molecule biophysics
Online Access:https://www.mdpi.com/1422-0067/24/23/17083

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