Lu-177-PSMA dosimetry for kidneys and tumors based on SPECT images at two imaging time points

Lu-177-PSMA dosimetry for kidneys and tumors based on SPECT images at two imaging time points

BackgroundPersonalized dosimetry for Lu-177-PSMA treatment requires multiple-time-point SPECT/CT scans to calculate time-integrated activity (TIA). This study evaluates two-time-point (TTP) methods for TIA calculation for kidneys and tumors.MethodsA total of 18 patients treated with 3.7-7.4 GBq Lu-1...

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Bibliographic Details
Main Authors: Gefei Chen, Zhonglin Lu, Han Jiang, Ali Afshar-Oromieh, Axel Rominger, Kuangyu Shi, Greta S. P. Mok
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Medicine
Subjects:
SPECT
Lu-177 PSMA
curve fitting
single time point
dosimetry
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1246881/full

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https://www.frontiersin.org/articles/10.3389/fmed.2023.1246881/full

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