Acetate-Mediated Odorant Receptor OR51E2 Activation Results in Calcitonin Secretion in Parafollicular C-Cells: A Novel Diagnostic Target of Human Medullary Thyroid Cancer

Acetate-Mediated Odorant Receptor OR51E2 Activation Results in Calcitonin Secretion in Parafollicular C-Cells: A Novel Diagnostic Target of Human Medullary Thyroid Cancer

Medullary thyroid cancer originates from parafollicular C-cells in the thyroid. Despite successful thyroidectomy, localizing remnant cancer cells in patients with elevated calcitonin and carcinoembryonic antigen levels remains a challenge. Extranasal odorant receptors are expressed in cells from non...

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Bibliographic Details
Main Authors:	Hyeon Jeong Lee, Cheol Ryong Ku, Arthur Cho, TaeHo Cho, ChaeEun Lee, Chan Woo Kang, Daham Kim, Yoon Hee Cho, JaeHyung Koo, Eun Jig Lee
Format:	Article
Language:	English
Published:	MDPI AG 2023-06-01
Series:	Biomedicines
Subjects:	odorant receptors acetate calcitonin parafollicular C-cells medullary thyroid cancer positron emission tomography
Online Access:	https://www.mdpi.com/2227-9059/11/6/1688

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