Common variable hypogammaglobulinemia: The author's observation
The paper gives a case history of a patient with common variable hypogammaglobulinemia (СVHGG). Its clinical picture was characterized by frequent inflammatory airway diseases, pansinusitis, and periodic rises in temperature up to febrile ones. The diagnosis was established on the basis of the decre...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
"Consilium Medicum" Publishing house
2015-01-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/31696 |
| _version_ | 1819022194996412416 |
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| author | A I Parfenov L M Krums O V Akhmadullina P L Shcherbakov S G Khomeriki N V Orlova E A Sabel'nikova N A Fadeeva |
| author_facet | A I Parfenov L M Krums O V Akhmadullina P L Shcherbakov S G Khomeriki N V Orlova E A Sabel'nikova N A Fadeeva |
| author_sort | A I Parfenov |
| collection | DOAJ |
| description | The paper gives a case history of a patient with common variable hypogammaglobulinemia (СVHGG). Its clinical picture was characterized by frequent inflammatory airway diseases, pansinusitis, and periodic rises in temperature up to febrile ones. The diagnosis was established on the basis of the decreased serum concentrations of immunoglobulins (IG) A, M, and G, the unusual small intestinal (SI) wall relief created by large lymphoid follicles, as well as the characteristic sign of CVHGG, namely, the lack of plasma cells in the lamina propria of the SI mucosa. Antibacterial therapy was noted to have a good effect that confirmed the leading role of excessive bacterial growth in the pathogenesis of chronic diarrhea and fever, which are the major clinical manifestations of CVHGG in this patient. |
| first_indexed | 2024-12-21T04:19:08Z |
| format | Article |
| id | doaj.art-8557d36e58d34757bc46c6107b273c0b |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-21T04:19:08Z |
| publishDate | 2015-01-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-8557d36e58d34757bc46c6107b273c0b2022-12-21T19:16:13Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422015-01-01871979928712Common variable hypogammaglobulinemia: The author's observationA I ParfenovL M KrumsO V AkhmadullinaP L ShcherbakovS G KhomerikiN V OrlovaE A Sabel'nikovaN A FadeevaThe paper gives a case history of a patient with common variable hypogammaglobulinemia (СVHGG). Its clinical picture was characterized by frequent inflammatory airway diseases, pansinusitis, and periodic rises in temperature up to febrile ones. The diagnosis was established on the basis of the decreased serum concentrations of immunoglobulins (IG) A, M, and G, the unusual small intestinal (SI) wall relief created by large lymphoid follicles, as well as the characteristic sign of CVHGG, namely, the lack of plasma cells in the lamina propria of the SI mucosa. Antibacterial therapy was noted to have a good effect that confirmed the leading role of excessive bacterial growth in the pathogenesis of chronic diarrhea and fever, which are the major clinical manifestations of CVHGG in this patient.https://ter-arkhiv.ru/0040-3660/article/view/31696immunoglobulinscommon variable hypogammaglobulinemianodular lymphoid hyperplasiaplasma cellsexcessive bacterial growth in the small intestine |
| spellingShingle | A I Parfenov L M Krums O V Akhmadullina P L Shcherbakov S G Khomeriki N V Orlova E A Sabel'nikova N A Fadeeva Common variable hypogammaglobulinemia: The author's observation Терапевтический архив immunoglobulins common variable hypogammaglobulinemia nodular lymphoid hyperplasia plasma cells excessive bacterial growth in the small intestine |
| title | Common variable hypogammaglobulinemia: The author's observation |
| title_full | Common variable hypogammaglobulinemia: The author's observation |
| title_fullStr | Common variable hypogammaglobulinemia: The author's observation |
| title_full_unstemmed | Common variable hypogammaglobulinemia: The author's observation |
| title_short | Common variable hypogammaglobulinemia: The author's observation |
| title_sort | common variable hypogammaglobulinemia the author s observation |
| topic | immunoglobulins common variable hypogammaglobulinemia nodular lymphoid hyperplasia plasma cells excessive bacterial growth in the small intestine |
| url | https://ter-arkhiv.ru/0040-3660/article/view/31696 |
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