HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection

HCV Genetic Diversity Can Be Used to Infer Infection Recency and Time since Infection

HIV-1 genetic diversity can be used to infer time since infection (TSI) and infection recency. We adapted this approach for HCV and identified genomic regions with informative diversity. We included 72 HCV/HIV-1 coinfected participants of the Swiss HIV Cohort Study, for whom reliable estimates of in...

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Bibliographic Details
Main Authors: Louisa A. Carlisle, Teja Turk, Karin J. Metzner, Herbert A. Mbunkah, Cyril Shah, Jürg Böni, Michael Huber, Dominique L. Braun, Jan Fehr, Luisa Salazar-Vizcaya, Andri Rauch, Sabine Yerly, Aude Nguyen, Matthias Cavassini, Marcel Stoeckle, Pietro Vernazza, Enos Bernasconi, Huldrych F. Günthard, Roger D. Kouyos
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
hepatitis C virus infection
infection recency
genetic variation
sequence analysis
viral genomics
Online Access:https://www.mdpi.com/1999-4915/12/11/1241

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