Maternal cold exposure induces distinct transcriptome changes in the placenta and fetal brown adipose tissue in mice

Maternal cold exposure induces distinct transcriptome changes in the placenta and fetal brown adipose tissue in mice

Abstract Background Brown adipose tissue (BAT) is specialized to dissipate energy in the form of heat. BAT-mediated heat production in rodents and humans is critical for effective temperature adaptation of newborns to the extrauterine environment immediately after birth. However, very little is know...

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Bibliographic Details
Main Authors: Sujoy Ghosh, Chul-Hong Park, Jisu Lee, Nathan Lee, Rui Zhang, Clara Huesing, Dorien Reijnders, Jennifer Sones, Heike Münzberg, Leanne Redman, Ji Suk Chang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Genomics
Subjects:
Brown adipose tissue thermogenesis
Fetal brown adipogenesis
Placenta
RNA-sequencing
Gene expression
Maternal-fetal crosstalk
Online Access:https://doi.org/10.1186/s12864-021-07825-6

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