Intravitreal Ranibizumab in the Treatment of Butterfly-Shaped Pattern Dystrophy Associated with Choroidal Neovascularization: A Case Report

Purpose: To present and document the effectiveness of intravitreal ranibizumab in the treatment of patients with choroidal neovascularization due to butterfly-shaped pattern dystrophy (PD) of the macula. Methods: Three intravitreal ranibizumab injections of 0.5 mg/0.05 ml in monthly intervals were g...

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Main Authors: Theodoros Empeslidis, Athanasios Vardarinos, James Deane, Somnath Banerjee
Format: Article
Language:English
Published: Karger Publishers 2012-02-01
Series:Case Reports in Ophthalmology
Subjects:
Online Access:http://www.karger.com/Article/FullText/336987
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author Theodoros Empeslidis
Athanasios Vardarinos
James Deane
Somnath Banerjee
author_facet Theodoros Empeslidis
Athanasios Vardarinos
James Deane
Somnath Banerjee
author_sort Theodoros Empeslidis
collection DOAJ
description Purpose: To present and document the effectiveness of intravitreal ranibizumab in the treatment of patients with choroidal neovascularization due to butterfly-shaped pattern dystrophy (PD) of the macula. Methods: Three intravitreal ranibizumab injections of 0.5 mg/0.05 ml in monthly intervals were given to a patient with a previously diagnosed butterfly-shaped PD who subsequently developed subfoveal choroidal neovascularization on the right eye. The patient had previously received a combination of verteporfin/photodynamic therapy for a juxtafoveal choroidal neovascular membrane on the left eye. Results: At the end of the treatment course, there was significant improvement of the patient’s vision and the appearance of the macula on optic coherence tomography and fluorescein angiography. Best-corrected visual acuity improved from 6/12 to 6/6 and retinal thickness at the macula decreased from 323 to 247 µm. No subretinal fluid remained. The patient is clinically stable over a 12-month follow-up period. Conclusions: Intravitreal ranibizumab seems to be an effective and safe option for the treatment of subfoveal choroidal neovascularization in patients with butterfly-shaped PD.
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spelling doaj.art-8567a59c96dd479d846285175a70086b2022-12-22T00:48:17ZengKarger PublishersCase Reports in Ophthalmology1663-26992012-02-0131778210.1159/000336987336987Intravitreal Ranibizumab in the Treatment of Butterfly-Shaped Pattern Dystrophy Associated with Choroidal Neovascularization: A Case ReportTheodoros EmpeslidisAthanasios VardarinosJames DeaneSomnath BanerjeePurpose: To present and document the effectiveness of intravitreal ranibizumab in the treatment of patients with choroidal neovascularization due to butterfly-shaped pattern dystrophy (PD) of the macula. Methods: Three intravitreal ranibizumab injections of 0.5 mg/0.05 ml in monthly intervals were given to a patient with a previously diagnosed butterfly-shaped PD who subsequently developed subfoveal choroidal neovascularization on the right eye. The patient had previously received a combination of verteporfin/photodynamic therapy for a juxtafoveal choroidal neovascular membrane on the left eye. Results: At the end of the treatment course, there was significant improvement of the patient’s vision and the appearance of the macula on optic coherence tomography and fluorescein angiography. Best-corrected visual acuity improved from 6/12 to 6/6 and retinal thickness at the macula decreased from 323 to 247 µm. No subretinal fluid remained. The patient is clinically stable over a 12-month follow-up period. Conclusions: Intravitreal ranibizumab seems to be an effective and safe option for the treatment of subfoveal choroidal neovascularization in patients with butterfly-shaped PD.http://www.karger.com/Article/FullText/336987Intravitreal ranibizumabPattern dystrophy of the maculaChoroidal neovascular membraneChoroidal neovascularization
spellingShingle Theodoros Empeslidis
Athanasios Vardarinos
James Deane
Somnath Banerjee
Intravitreal Ranibizumab in the Treatment of Butterfly-Shaped Pattern Dystrophy Associated with Choroidal Neovascularization: A Case Report
Case Reports in Ophthalmology
Intravitreal ranibizumab
Pattern dystrophy of the macula
Choroidal neovascular membrane
Choroidal neovascularization
title Intravitreal Ranibizumab in the Treatment of Butterfly-Shaped Pattern Dystrophy Associated with Choroidal Neovascularization: A Case Report
title_full Intravitreal Ranibizumab in the Treatment of Butterfly-Shaped Pattern Dystrophy Associated with Choroidal Neovascularization: A Case Report
title_fullStr Intravitreal Ranibizumab in the Treatment of Butterfly-Shaped Pattern Dystrophy Associated with Choroidal Neovascularization: A Case Report
title_full_unstemmed Intravitreal Ranibizumab in the Treatment of Butterfly-Shaped Pattern Dystrophy Associated with Choroidal Neovascularization: A Case Report
title_short Intravitreal Ranibizumab in the Treatment of Butterfly-Shaped Pattern Dystrophy Associated with Choroidal Neovascularization: A Case Report
title_sort intravitreal ranibizumab in the treatment of butterfly shaped pattern dystrophy associated with choroidal neovascularization a case report
topic Intravitreal ranibizumab
Pattern dystrophy of the macula
Choroidal neovascular membrane
Choroidal neovascularization
url http://www.karger.com/Article/FullText/336987
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AT jamesdeane intravitrealranibizumabinthetreatmentofbutterflyshapedpatterndystrophyassociatedwithchoroidalneovascularizationacasereport
AT somnathbanerjee intravitrealranibizumabinthetreatmentofbutterflyshapedpatterndystrophyassociatedwithchoroidalneovascularizationacasereport