Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information

<p>Abstract</p> <p>Background</p> <p>As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational methods that can distinguish disease-causing SAPs from neutral SAPs are...

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Bibliographic Details
Main Authors: Yan Changhui, Hu Jing
Format: Article
Language:English
Published: BMC 2008-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/297