Release of cognitive and multimodal MRI data including real-world tasks and hippocampal subfield segmentations

Abstract We share data from N = 217 healthy adults (mean age 29 years, range 20–41; 109 females, 108 males) who underwent extensive cognitive assessment and neuroimaging to examine the neural basis of individual differences, with a particular focus on a brain structure called the hippocampus. Cognit...

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Main Authors: Ian A. Clark, Eleanor A. Maguire
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-023-02449-9
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author Ian A. Clark
Eleanor A. Maguire
author_facet Ian A. Clark
Eleanor A. Maguire
author_sort Ian A. Clark
collection DOAJ
description Abstract We share data from N = 217 healthy adults (mean age 29 years, range 20–41; 109 females, 108 males) who underwent extensive cognitive assessment and neuroimaging to examine the neural basis of individual differences, with a particular focus on a brain structure called the hippocampus. Cognitive data were collected using a wide array of questionnaires, naturalistic tests that examined imagination, autobiographical memory recall and spatial navigation, traditional laboratory-based tests such as recalling word pairs, and comprehensive characterisation of the strategies used to perform the cognitive tests. 3 Tesla MRI data were also acquired and include multi-parameter mapping to examine tissue microstructure, diffusion-weighted MRI, T2-weighted high-resolution partial volume structural MRI scans (with the masks of hippocampal subfields manually segmented from these scans), whole brain resting state functional MRI scans and partial volume high resolution resting state functional MRI scans. This rich dataset will be of value to cognitive and clinical neuroscientists researching individual differences, real-world cognition, brain-behaviour associations, hippocampal subfields and more. All data are freely available on Dryad.
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spelling doaj.art-856cfa9dcfb54dfdaafcda8190f6a7142023-11-19T12:19:54ZengNature PortfolioScientific Data2052-44632023-08-0110112910.1038/s41597-023-02449-9Release of cognitive and multimodal MRI data including real-world tasks and hippocampal subfield segmentationsIan A. Clark0Eleanor A. Maguire1Wellcome Centre for Human Neuroimaging, Department of Imaging Neuroscience, UCL Queen Square Institute of Neurology, University College LondonWellcome Centre for Human Neuroimaging, Department of Imaging Neuroscience, UCL Queen Square Institute of Neurology, University College LondonAbstract We share data from N = 217 healthy adults (mean age 29 years, range 20–41; 109 females, 108 males) who underwent extensive cognitive assessment and neuroimaging to examine the neural basis of individual differences, with a particular focus on a brain structure called the hippocampus. Cognitive data were collected using a wide array of questionnaires, naturalistic tests that examined imagination, autobiographical memory recall and spatial navigation, traditional laboratory-based tests such as recalling word pairs, and comprehensive characterisation of the strategies used to perform the cognitive tests. 3 Tesla MRI data were also acquired and include multi-parameter mapping to examine tissue microstructure, diffusion-weighted MRI, T2-weighted high-resolution partial volume structural MRI scans (with the masks of hippocampal subfields manually segmented from these scans), whole brain resting state functional MRI scans and partial volume high resolution resting state functional MRI scans. This rich dataset will be of value to cognitive and clinical neuroscientists researching individual differences, real-world cognition, brain-behaviour associations, hippocampal subfields and more. All data are freely available on Dryad.https://doi.org/10.1038/s41597-023-02449-9
spellingShingle Ian A. Clark
Eleanor A. Maguire
Release of cognitive and multimodal MRI data including real-world tasks and hippocampal subfield segmentations
Scientific Data
title Release of cognitive and multimodal MRI data including real-world tasks and hippocampal subfield segmentations
title_full Release of cognitive and multimodal MRI data including real-world tasks and hippocampal subfield segmentations
title_fullStr Release of cognitive and multimodal MRI data including real-world tasks and hippocampal subfield segmentations
title_full_unstemmed Release of cognitive and multimodal MRI data including real-world tasks and hippocampal subfield segmentations
title_short Release of cognitive and multimodal MRI data including real-world tasks and hippocampal subfield segmentations
title_sort release of cognitive and multimodal mri data including real world tasks and hippocampal subfield segmentations
url https://doi.org/10.1038/s41597-023-02449-9
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