Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy?
ABSTRACT Objective This prospective study evaluated the recurrence rate in low-risk patients with papillary thyroid cancer (PTC) who presented slightly elevated thyroglobulin (Tg) after thyroidectomy and who did not undergo ablation with131I. Subjects and methods The study included 53 low-risk p...
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| Format: | Article |
| Language: | English |
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Brazilian Society of Endocrinology and Metabolism
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| Series: | Archives of Endocrinology and Metabolism |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000100005&lng=en&tlng=en |
| _version_ | 1828741494563930112 |
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| author | Pedro Weslley Rosario Gabriela Franco Mourão |
| author_facet | Pedro Weslley Rosario Gabriela Franco Mourão |
| author_sort | Pedro Weslley Rosario |
| collection | DOAJ |
| description | ABSTRACT Objective This prospective study evaluated the recurrence rate in low-risk patients with papillary thyroid cancer (PTC) who presented slightly elevated thyroglobulin (Tg) after thyroidectomy and who did not undergo ablation with131I. Subjects and methods The study included 53 low-risk patients (nonaggressive histology; pT1b-3, cN0pNx, M0) with slightly elevated Tg after thyroidectomy (> 1 ng/mL, but ≤ 5 ng/mL after levothyroxine withdrawal or ≤ 2 ng/mL after recombinant human TSH). Results The time of follow-up ranged from 36 to 96 months. Lymph node metastases were detected in only one patient (1.9%). Fifty-two patients continued to present negative neck ultrasound. None of these patients without apparent disease presented an increase in Tg. Conclusions Low-risk patients with PTC who present slightly elevated Tg after thyroidectomy do not require ablation with 131I. |
| first_indexed | 2024-04-13T01:01:01Z |
| format | Article |
| id | doaj.art-856fa71fe34540fab55200f28e394693 |
| institution | Directory Open Access Journal |
| issn | 2359-4292 |
| language | English |
| last_indexed | 2024-04-13T01:01:01Z |
| publisher | Brazilian Society of Endocrinology and Metabolism |
| record_format | Article |
| series | Archives of Endocrinology and Metabolism |
| spelling | doaj.art-856fa71fe34540fab55200f28e3946932022-12-22T03:09:28ZengBrazilian Society of Endocrinology and MetabolismArchives of Endocrinology and Metabolism2359-42926015810.1590/2359-3997000000158S2359-39972016000100005Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy?Pedro Weslley RosarioGabriela Franco MourãoABSTRACT Objective This prospective study evaluated the recurrence rate in low-risk patients with papillary thyroid cancer (PTC) who presented slightly elevated thyroglobulin (Tg) after thyroidectomy and who did not undergo ablation with131I. Subjects and methods The study included 53 low-risk patients (nonaggressive histology; pT1b-3, cN0pNx, M0) with slightly elevated Tg after thyroidectomy (> 1 ng/mL, but ≤ 5 ng/mL after levothyroxine withdrawal or ≤ 2 ng/mL after recombinant human TSH). Results The time of follow-up ranged from 36 to 96 months. Lymph node metastases were detected in only one patient (1.9%). Fifty-two patients continued to present negative neck ultrasound. None of these patients without apparent disease presented an increase in Tg. Conclusions Low-risk patients with PTC who present slightly elevated Tg after thyroidectomy do not require ablation with 131I.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000100005&lng=en&tlng=enThyroid cancerlow-riskpostoperative thyroglobulinradioiodinerecurrence |
| spellingShingle | Pedro Weslley Rosario Gabriela Franco Mourão Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy? Archives of Endocrinology and Metabolism Thyroid cancer low-risk postoperative thyroglobulin radioiodine recurrence |
| title | Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy? |
| title_full | Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy? |
| title_fullStr | Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy? |
| title_full_unstemmed | Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy? |
| title_short | Is 131I ablation necessary for patients with low-risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy? |
| title_sort | is 131i ablation necessary for patients with low risk papillary thyroid carcinoma and slightly elevated stimulated thyroglobulin after thyroidectomy |
| topic | Thyroid cancer low-risk postoperative thyroglobulin radioiodine recurrence |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000100005&lng=en&tlng=en |
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