Critical appraisal of a clinical research paper: What one needs to know

In the present era of evidence-based medicine (EBM), integrating best research evidence into the clinical practice necessitates developing skills to critically evaluate and analyze the scientific literature. Critical appraisal is the process of systematically examining research evidence to assess it...

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Main Authors: Jifmi Jose Manjali, Tejpal Gupta
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Cancer Research, Statistics, and Treatment
Subjects:
Online Access:http://www.crstonline.com/article.asp?issn=2590-3233;year=2020;volume=3;issue=3;spage=545;epage=551;aulast=Manjali
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author Jifmi Jose Manjali
Tejpal Gupta
author_facet Jifmi Jose Manjali
Tejpal Gupta
author_sort Jifmi Jose Manjali
collection DOAJ
description In the present era of evidence-based medicine (EBM), integrating best research evidence into the clinical practice necessitates developing skills to critically evaluate and analyze the scientific literature. Critical appraisal is the process of systematically examining research evidence to assess its validity, results, and relevance to inform clinical decision-making. All components of a clinical research article need to be appraised as per the study design and conduct. As research bias can be introduced at every step in the flow of a study leading to erroneous conclusions, it is essential that suitable measures are adopted to mitigate bias. Several tools have been developed for the critical appraisal of scientific literature, including grading of evidence to help clinicians in the pursuit of EBM in a systematic manner. In this review, we discuss the broad framework for the critical appraisal of a clinical research paper, along with some of the relevant guidelines and recommendations.
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spelling doaj.art-856fab6752c94a5e9d511266903e3f0f2022-12-21T23:41:44ZengWolters Kluwer Medknow PublicationsCancer Research, Statistics, and Treatment2590-32332590-32252020-01-013354555110.4103/CRST.CRST_211_20Critical appraisal of a clinical research paper: What one needs to knowJifmi Jose ManjaliTejpal GuptaIn the present era of evidence-based medicine (EBM), integrating best research evidence into the clinical practice necessitates developing skills to critically evaluate and analyze the scientific literature. Critical appraisal is the process of systematically examining research evidence to assess its validity, results, and relevance to inform clinical decision-making. All components of a clinical research article need to be appraised as per the study design and conduct. As research bias can be introduced at every step in the flow of a study leading to erroneous conclusions, it is essential that suitable measures are adopted to mitigate bias. Several tools have been developed for the critical appraisal of scientific literature, including grading of evidence to help clinicians in the pursuit of EBM in a systematic manner. In this review, we discuss the broad framework for the critical appraisal of a clinical research paper, along with some of the relevant guidelines and recommendations.http://www.crstonline.com/article.asp?issn=2590-3233;year=2020;volume=3;issue=3;spage=545;epage=551;aulast=Manjaliappraisalbiasclinical studyevidence-based medicineguidelinestools
spellingShingle Jifmi Jose Manjali
Tejpal Gupta
Critical appraisal of a clinical research paper: What one needs to know
Cancer Research, Statistics, and Treatment
appraisal
bias
clinical study
evidence-based medicine
guidelines
tools
title Critical appraisal of a clinical research paper: What one needs to know
title_full Critical appraisal of a clinical research paper: What one needs to know
title_fullStr Critical appraisal of a clinical research paper: What one needs to know
title_full_unstemmed Critical appraisal of a clinical research paper: What one needs to know
title_short Critical appraisal of a clinical research paper: What one needs to know
title_sort critical appraisal of a clinical research paper what one needs to know
topic appraisal
bias
clinical study
evidence-based medicine
guidelines
tools
url http://www.crstonline.com/article.asp?issn=2590-3233;year=2020;volume=3;issue=3;spage=545;epage=551;aulast=Manjali
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