NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells

NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells

Abstract Background Medulloblastoma (MB) is the most common pediatric malignant brain tumor. Despite current therapies, the morbidity and recurrent risk remains significant. Neuropilin-1 receptor (NRP1) has been implicated in the tumor progression of MB. Our recent study showed that NRP1 inhibition...

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Bibliographic Details
Main Authors: Manon Douyère, Caifeng Gong, Mylène Richard, Nadia Pellegrini-Moïse, Joël Daouk, Julien Pierson, Pascal Chastagner, Cédric Boura
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Cell International
Subjects:
Medulloblastoma
Neuropilin-1
Cancer stem cells
Radiotherapy
Online Access:https://doi.org/10.1186/s12935-022-02796-4

Internet

https://doi.org/10.1186/s12935-022-02796-4

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