Angiogenic Potential in Biological Hydrogels
Hydrogels are three-dimensional (3D) materials able to absorb and retain water in large amounts while maintaining their structural stability. Due to their considerable biocompatibility and similarity with the body’s tissues, hydrogels are one of the most promising groups of biomaterials. The main ap...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/8/10/436 |
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| author | Maria Vittoria Giraudo Dalila Di Francesco Marta Calvo Catoira Diego Cotella Luca Fusaro Francesca Boccafoschi |
| author_facet | Maria Vittoria Giraudo Dalila Di Francesco Marta Calvo Catoira Diego Cotella Luca Fusaro Francesca Boccafoschi |
| author_sort | Maria Vittoria Giraudo |
| collection | DOAJ |
| description | Hydrogels are three-dimensional (3D) materials able to absorb and retain water in large amounts while maintaining their structural stability. Due to their considerable biocompatibility and similarity with the body’s tissues, hydrogels are one of the most promising groups of biomaterials. The main application of these hydrogels is in regenerative medicine, in which they allow the formation of an environment suitable for cell differentiation and growth. Deriving from these hydrogels, it is, therefore, possible to obtain bioactive materials that can regenerate tissues. Because vessels guarantee the right amount of oxygen and nutrients but also assure the elimination of waste products, angiogenesis is one of the processes at the base of the regeneration of a tissue. On the other hand, it is a very complex mechanism and the parameters to consider are several. Indeed, the factors and the cells involved in this process are numerous and, for this reason, it has been a challenge to recreate a biomaterial able to adequately sustain the angiogenic process. However, in this review the focal point is the application of natural hydrogels in angiogenesis enhancing and their potential to guide this process. |
| first_indexed | 2024-03-10T15:29:39Z |
| format | Article |
| id | doaj.art-857a13528e974485add6ba5d6ac7f417 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-10T15:29:39Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-857a13528e974485add6ba5d6ac7f4172023-11-20T17:46:04ZengMDPI AGBiomedicines2227-90592020-10-0181043610.3390/biomedicines8100436Angiogenic Potential in Biological HydrogelsMaria Vittoria Giraudo0Dalila Di Francesco1Marta Calvo Catoira2Diego Cotella3Luca Fusaro4Francesca Boccafoschi5Department of Health Sciences, University of Piemonte Orientale, 28100 Novara, ItalyDepartment of Health Sciences, University of Piemonte Orientale, 28100 Novara, ItalyTissuegraft srl, 28100 Novara, ItalyDepartment of Health Sciences, University of Piemonte Orientale, 28100 Novara, ItalyTissuegraft srl, 28100 Novara, ItalyDepartment of Health Sciences, University of Piemonte Orientale, 28100 Novara, ItalyHydrogels are three-dimensional (3D) materials able to absorb and retain water in large amounts while maintaining their structural stability. Due to their considerable biocompatibility and similarity with the body’s tissues, hydrogels are one of the most promising groups of biomaterials. The main application of these hydrogels is in regenerative medicine, in which they allow the formation of an environment suitable for cell differentiation and growth. Deriving from these hydrogels, it is, therefore, possible to obtain bioactive materials that can regenerate tissues. Because vessels guarantee the right amount of oxygen and nutrients but also assure the elimination of waste products, angiogenesis is one of the processes at the base of the regeneration of a tissue. On the other hand, it is a very complex mechanism and the parameters to consider are several. Indeed, the factors and the cells involved in this process are numerous and, for this reason, it has been a challenge to recreate a biomaterial able to adequately sustain the angiogenic process. However, in this review the focal point is the application of natural hydrogels in angiogenesis enhancing and their potential to guide this process.https://www.mdpi.com/2227-9059/8/10/436hydrogelnatural polymersdecellularized matrix |
| spellingShingle | Maria Vittoria Giraudo Dalila Di Francesco Marta Calvo Catoira Diego Cotella Luca Fusaro Francesca Boccafoschi Angiogenic Potential in Biological Hydrogels Biomedicines hydrogel natural polymers decellularized matrix |
| title | Angiogenic Potential in Biological Hydrogels |
| title_full | Angiogenic Potential in Biological Hydrogels |
| title_fullStr | Angiogenic Potential in Biological Hydrogels |
| title_full_unstemmed | Angiogenic Potential in Biological Hydrogels |
| title_short | Angiogenic Potential in Biological Hydrogels |
| title_sort | angiogenic potential in biological hydrogels |
| topic | hydrogel natural polymers decellularized matrix |
| url | https://www.mdpi.com/2227-9059/8/10/436 |
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