The Structure and Activity of Double-Nitroimidazoles. A Mini-Review

Many interesting applications have been found for nitroimidazoles as therapeutic agents. Among others, some of these compounds can radiosensitize hypoxic tumor cells. The introduction of a second nitroimidazole ring to the molecule can improve the level of its pharmacological effect. The aim of this...

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Bibliographic Details
Main Authors: Justyna Żwawiak, Lucjusz Zaprutko
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Scientia Pharmaceutica
Subjects:
Online Access:http://www.mdpi.com/2218-0532/86/3/30
Description
Summary:Many interesting applications have been found for nitroimidazoles as therapeutic agents. Among others, some of these compounds can radiosensitize hypoxic tumor cells. The introduction of a second nitroimidazole ring to the molecule can improve the level of its pharmacological effect. The aim of this article is to overview the literature concerning active compounds that contain two nitroimidazole moieties in their structures.
ISSN:2218-0532