Serum calcitonin negative Medullary thyroid carcinoma
<p>Abstract</p> <p>Background</p> <p>Medullary thyroid carcinomas (MTC) constitute about 5 to 7 % of thyroid neoplasms. They originate from parafollicular C cells which produce Calcitonin, a hormone which has an impact on calcium metabolism and represents the biochemica...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
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BMC
2006-12-01
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Series: | World Journal of Surgical Oncology |
Online Access: | http://www.wjso.com/content/4/1/97 |
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author | Welsing Ellen Bonhag Gerd Bechara Falk G Sand Daniel Gelos Marcos Sand Michael Mann Benno |
author_facet | Welsing Ellen Bonhag Gerd Bechara Falk G Sand Daniel Gelos Marcos Sand Michael Mann Benno |
author_sort | Welsing Ellen |
collection | DOAJ |
description | <p>Abstract</p> <p>Background</p> <p>Medullary thyroid carcinomas (MTC) constitute about 5 to 7 % of thyroid neoplasms. They originate from parafollicular C cells which produce Calcitonin, a hormone which has an impact on calcium metabolism and represents the biochemical activity of MTC. In rare cases pre-operative serum calcitonin can be negative.</p> <p>Case presentation</p> <p>We report on a 73-year-old female patient with a rare case of a serum calcitonin negative medullary thyroid carcinoma who suffered fulminant post-operative course and died of multiple metastasis.</p> <p>Conclusion</p> <p>This case shows that in very rare cases MTCs do not secrete calcitonin making diagnosis and tumour follow-up difficult. To this date, only few reports describing this combination of circumstances were found in the English literature.</p> |
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format | Article |
id | doaj.art-857c26f0f8424bc19431a4d58abc5d0c |
institution | Directory Open Access Journal |
issn | 1477-7819 |
language | English |
last_indexed | 2024-12-10T10:56:56Z |
publishDate | 2006-12-01 |
publisher | BMC |
record_format | Article |
series | World Journal of Surgical Oncology |
spelling | doaj.art-857c26f0f8424bc19431a4d58abc5d0c2022-12-22T01:51:50ZengBMCWorld Journal of Surgical Oncology1477-78192006-12-01419710.1186/1477-7819-4-97Serum calcitonin negative Medullary thyroid carcinomaWelsing EllenBonhag GerdBechara Falk GSand DanielGelos MarcosSand MichaelMann Benno<p>Abstract</p> <p>Background</p> <p>Medullary thyroid carcinomas (MTC) constitute about 5 to 7 % of thyroid neoplasms. They originate from parafollicular C cells which produce Calcitonin, a hormone which has an impact on calcium metabolism and represents the biochemical activity of MTC. In rare cases pre-operative serum calcitonin can be negative.</p> <p>Case presentation</p> <p>We report on a 73-year-old female patient with a rare case of a serum calcitonin negative medullary thyroid carcinoma who suffered fulminant post-operative course and died of multiple metastasis.</p> <p>Conclusion</p> <p>This case shows that in very rare cases MTCs do not secrete calcitonin making diagnosis and tumour follow-up difficult. To this date, only few reports describing this combination of circumstances were found in the English literature.</p>http://www.wjso.com/content/4/1/97 |
spellingShingle | Welsing Ellen Bonhag Gerd Bechara Falk G Sand Daniel Gelos Marcos Sand Michael Mann Benno Serum calcitonin negative Medullary thyroid carcinoma World Journal of Surgical Oncology |
title | Serum calcitonin negative Medullary thyroid carcinoma |
title_full | Serum calcitonin negative Medullary thyroid carcinoma |
title_fullStr | Serum calcitonin negative Medullary thyroid carcinoma |
title_full_unstemmed | Serum calcitonin negative Medullary thyroid carcinoma |
title_short | Serum calcitonin negative Medullary thyroid carcinoma |
title_sort | serum calcitonin negative medullary thyroid carcinoma |
url | http://www.wjso.com/content/4/1/97 |
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