Identification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite Protein.

Identification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite Protein.

Malaria vaccine development has been hampered by the limited availability of antigens identified through conventional discovery approaches, and improvements are needed to enhance the efficacy of the leading vaccine candidate RTS,S that targets the circumsporozoite protein (CSP) of the infective spor...

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Main Authors: Cate Speake, Alexander Pichugin, Tejram Sahu, Vlad Malkov, Robert Morrison, Ying Pei, Laure Juompan, Neta Milman, Stasya Zarling, Charles Anderson, Sharon Wong-Madden, Jason Wendler, Andrew Ishizuka, Zachary W MacMillen, Valentino Garcia, Stefan H I Kappe, Urszula Krzych, Patrick E Duffy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4951032?pdf=render

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