Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells

Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells

Abstract Background Development of multidrug resistance (MDR) is a major burden of successful chemotherapy, therefore, novel approaches to defeat MDR are imperative. Although the remarkable anti-cancer propensity of silver nanoparticles (AgNP) has been demonstrated and their potential application in...

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Bibliographic Details
Main Authors: Mohana Krishna Gopisetty, Dávid Kovács, Nóra Igaz, Andrea Rónavári, Péter Bélteky, Zsolt Rázga, Viktória Venglovecz, Bálint Csoboz, Imre Miklós Boros, Zoltán Kónya, Mónika Kiricsi
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Nanobiotechnology
Subjects:
Silver nanoparticles
Multidrug resistance
P-glycoprotein
ER stress
Online Access:http://link.springer.com/article/10.1186/s12951-019-0448-4

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